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CSR's Powers Retires After 22 Years

By Don Luckett

Dr. Marcelina Powers recently cleared her desk at the Center for Scientific Review. After 22 years of federal service, she was looking forward to retiring. She has been the scientific review administrator for one of CSR's busiest study sections — the metabolic pathology study section of the oncological sciences integrated review group — since its inception in 1984. Powers, however, went about her final duties with a gentle, satisfied smile. Through her many efforts as an SRA, she has helped accelerate important cancer research and bring new investigators into the field.

Dr. Marcelina Powers

She has accomplished much since she and her family survived the occupation and liberation of the Philippines in World War II. She earned her D.V.M. degree from the University of the Philippines, becoming the third female veterinarian in the country. She then made the biggest move of her life, flying to the United States in 1957 to accept a research assistantship at the University of Wisconsin in Madison. After receiving a master's degree in veterinary science there, she became director of toxicology for the Wisconsin Alumni Research Foundation. She eventually moved to Hazleton Laboratories in Falls Church, Va., where she was director of toxicology for 15 years.

Powers joined the National Cancer Institute in 1978 as a program director in the Bioassay Program, coordinating the toxicology testing of potential cancer drugs at 3-4 contract laboratories. When a new SRA was needed to develop the metabolic pathology study section at CSR, she accepted the challenge and adeptly managed its increasing workload for 16 years. Dr. Syed Quadri, chief of the oncological sciences IRG, said that Powers will be greatly missed because "she has been a thoughtful advisor to many SRAs in CSR, especially the oncological sciences IRG members." He also praised Powers for her "outstandingly valuable" interactions with the extramural scientific community over the years.

Powers was thus able to count many accomplishments and friends at NIH as she closed her office door for the last time on Dec. 31, 2000. She also could count many enjoyments for her new life ahead. She looks forward to reading more novels, gardening and continuing aerobic classes with friends at the YMCA. She also plans to visit her son in Denver and her family in the Philippines, and travel more with her husband.

NINDS's Brinley Retires After More Than Two Decades

By Shannon E. Garnett

Dr. Floyd John Brinley, Jr., associate director of infection and immunity, NINDS, recently retired after 23 years of government service — all with NIH.

"Jack Brinley has served this institute and the neuroscience community with great distinction," said then NINDS director Dr. Gerald Fischbach. "His overview of the field and judgement were of great value to me when I joined NINDS. He has left his mark on the field."

Dr. Floyd John Brinley, Jr.

For years Brinley was instrumental in helping to lead NINDS's extramural division. From 1979 to 1982, he was head of the institute's Neurological Disorders Program — a large extramural research program that supported studies on a broad spectrum of diseases and disorders. In this role, he was in charge of guiding the institute's research grants, contracts and fellowships that supported basic research in areas such as developmental disorders, Parkinson's disease, Huntington's disease, Alzheimer's disease, convulsive disorders including epilepsy and sleep research, multiple sclerosis, amyotrophic lateral sclerosis, neuromuscular disorders, infections, neuroendocrine disorders and neurotoxicology.

In 1982, when the program was divided into two smaller components — the Division of Convulsive, Developmental, and Neuromuscular Disorders (DCDND) and the Division of Demyelinating, Atrophic, and Dementing Disorders — he became director of DCDND. Later, in 1995, the divisions were reorganized and Brinley became director of the Division of Convulsive, Infectious, and Immune Disorders — retaining oversight of the epilepsy, sleep, and neuromuscular disorders research grants, adding multiple sclerosis and AIDS grants, and losing developmental disorders grants, which became part of the fundamental neuroscience division. In 1999, he was named associate director of infection and immunity, with special interests in HIV-1 infection and prion diseases.

A native of Battle Creek, Mich., Brinley earned his bachelor of arts degree from Oberlin College in 1951, and his medical degree from the University of Michigan in 1955. He then interned at the Los Angeles County General Hospital until 1956. He first came to NIH in 1957 as a senior assistant surgeon in the Laboratory of Neurophysiology — a lab jointly run by NIMH and NINDB (now NINDS). He left in 1959 to continue graduate studies at Johns Hopkins University, where he earned his Ph.D. in biophysics in 1961.

He began his professional career at Hopkins in 1961, serving as an assistant professor of physiology, and as an associate professor in 1966. Before coming to NINDS in 1979, Brinley taught at the University of Maryland School of Medicine as a professor of physiology.

Despite his busy schedule at NINDS, he continued to impart his knowledge to others by serving as a visiting professor of biophysics at the University of Maryland School of Medicine from 1981 to 1995.

Throughout his career, Brinley has received numerous accolades and honors including awards for his service and participation in the Public Health Service Commissioned Corp. For many years he was commander of the NIH disaster medical assistance team.

He has memberships in many professional societies including the Society of General Physiologists, the American Physiological Society and the American Society of Biological Chemists, and has served on the editorial boards of such journals as the Journal of Neurophysiology, Cell Calcium, and Cellular and Molecular Neurobiology.

CSR's Sam Joseloff Retires

By Don Luckett

"Every day is a new day, and I focus on the enjoyable aspects of that day," said Dr. Samuel H. Joseloff, who recently retired from the Center for Scientific Review after almost 22 years at NIH. At CSR, he was a public affairs specialist who also served as executive secretary for the CSR advisory committee, CSR information officer, and the center's Freedom of Information Act and Privacy Act coordinator.

Joseloff has lived by his philosophy. Colleagues say he brought a fresh approach to every problem and found adventure and good company wherever he went. Indeed, his ability to try and enjoy new things led him on a most unusual path to NIH.

Dr. Samuel H. Joseloff

His surprising journey began in the English departments of Yale University, the University of Wisconsin and Princeton University, where he developed a passion for 18th Century English literature. He earned two master's degrees and a Ph.D. In 1968, he accepted a term appointment as an assistant professor of English at Georgetown University. In addition to teaching the traditional courses there, he developed a program in Jewish literature. He thoroughly enjoyed teaching, but kept his options open.

A chance encounter brought him an unexpected offer to become head of publications for the National Biomedical Research Foundation at Georgetown University Medical Center. The challenge intrigued him, and Joseloff became fascinated with the potential of using his skills in an exciting new field. With a sense of adventure, he went to work editing scientific articles and preparing a newsletter. He even developed an operating manual for the ACTA Scanner, the first whole-body, CAT, X-ray scan machine. He found similar challenges as head of documentations at a consulting firm, CDP Associates, in 1978.

His career path took a defining turn a year later, when he became special assistant to the associate director of referral and review at the Division of Research Grants, which is now CSR. After developing orientation handbooks for peer reviewers, an extensive slide collection, videotapes, a history of DRG, and other projects, Joseloff was "hooked" on the work and people at NIH. In 1984, he moved to the National Heart, Lung and Blood Institute to be executive secretary of its advisory council. He returned to DRG in 1996 to head the Office of Grant Inquiries, and eventually came to the Office of the CSR Director.

Colleagues and coworkers could always count on him. Joseloff provided just the right words in writing and editing CSR documents. Dr. Ellie Ehrenfeld, CSR director, said "he will be sincerely missed by CSR staff and its advisory committee members as well as by the extramural scientific community."

Joseloff now has a to-do list that could occupy three retirees — music, hobbies, volunteer work, and writing and editing. It is hard to say where this new path will take him. One thing, however, is guaranteed: every day will be a new day with something to be enjoyed.


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