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Women with Premature Ovarian Failure Needed
Researchers at NICHD are recruiting women who have premature ovarian failure — formerly known as premature menopause — to determine if restoring testosterone will help prevent osteoporosis.

According to Dr. Lawrence M. Nelson, head of NICHD's unit on gynecologic endocrinology, the women will receive testosterone in addition to the combination of replacement hormones (estrogen and progestin) prescribed for women with premature ovarian failure. The testosterone will be delivered through a patch worn on the skin. "Many women who experience premature ovarian failure don't realize how important it is to replace the hormones that the ovary no longer provides," he said. "We're testing a new method to improve replacing these ovarian hormones."

Women who volunteer for the study will have the opportunity to come to NIH to be evaluated by a team of experts in premature ovarian failure. The evaluation will be provided at no charge, and, in most cases, patients will be reimbursed for their travel expenses.

For information on how to participate in the study, potential volunteers with premature ovarian failure — as well as women with normally functioning ovaries — between the ages of 18 and 42 may contact Vien Vanderhoof by calling toll free at (877) 206-0911.

Female Volunteers Needed
The Behavioral Endocrinology Branch, NIMH, is seeking female volunteers ages 18-55 to participate in studies of the effects of menstrual cycle hormones on brain and behavior. Volunteers must have regular menstrual cycles with no changes in mood in relationship to menses, be free of medical illnesses and not taking any hormones or medication on a regular basis. They will complete daily rating forms and be offered participation in one or more protocols. Payment will be in accordance with the duration of each visit and the type of protocol. For more information, call Linda Simpson-St. Clair, 496-9576.

Nonsmoking Volunteers Needed
Are you a female nonsmoker, 18 to 35 years old, in good health and not on birth control pills? You may be eligible to participate in a study of commonly prescribed medications. The study involves multiple visits to the Uniformed Services University (next to the Naval Medical Center, across the pike from NIH) over a 3-month period. Earn up to $880 and get a free physical exam. Call (301) 319-8204 for more information and a preliminary telephone screening.

Postpartum Depression Study
The Behavioral Endocrinology Branch, NIMH, is seeking female volunteer mothers ages 18-40 who: have had one or more past episodes of postpartum depression following a full-term pregnancy, have no current symptoms of depression, must be 6 months post-delivery and not lactating, must be medically healthy and medication-free. Volunteers may be asked to participate in a 6-month protocol investigating the effects of ovarian and stress hormones on brain and behavior. Payment is provided for those who complete the study. For more information call Linda Simpson-St. Clair, 496-9576.


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