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Crohn's Disease Disrupting Your Life?

If so, consider taking part in a study to test the safety and effectiveness of a potential new Crohn's disease treatment against a placebo (a substance that neither harms nor helps). The study takes place at the Clinical Center. If you are age 18 or older with moderate Crohn's symptoms, call for more information. There is no charge for study-related testing or medicine. For more information, call toll-free 1-800-411-1222 (TTY: 866-411-1010).

Postpartum Depression Study

The Behavioral Endocrinology Branch, NIMH, is seeking female volunteer mothers ages 18-40 who: have had one or more past episodes of postpartum depression following a full-term pregnancy, have no current symptoms of depression, must be 6 months post-delivery and not lactating, must be medically healthy and medication-free. Volunteers may be asked to participate in a 6-month protocol investigating the effects of ovarian and stress hormones on brain and behavior. Payment is provided for those who complete the study. For more information call Linda Simpson-St. Clair, 496-9576.

Menopause Study Needs Women

NICHD invites healthy women, ages 45-70, to participate in a study of a new investigational hormonal treatment for menopause. You may be eligible if you are not diabetic, had no menstrual periods for at least 1 year, do not take hormone replacement therapy, do not smoke and have not had a hysterectomy. Participation involves brief weekly outpatient visits. Call 1-800-411-1222 (TTY 1-866-411-1010).

Chronic Back and Leg Pain

The NIH Pain Research Clinic is conducting research studies to improve the treatment of chronic back and leg pain. Clinicians are interested in pain resulting from a pinched lumbar nerve caused by conditions such as a herniated disc, a bone spur or arthritis. You may be able to take part if you are age 18 or older and if you have had pain in your back and leg or buttock for the last 3 months. The study takes place at the Clinical Center. All study-related tests and medicines are provided free of charge. For more information, call toll-free: 1-800-411-1222 (TTY: 1-866-411-1010).

Healthy Women Needed for Study

NICHD is seeking women, ages 18-42, to participate in a research study comparing bone density in healthy women. You may be eligible if you have no medical conditions, or an irregular menstrual cycle, not pregnant, nursing or planning pregnancy over the next 3 years, do not use oral contraceptives or prescribed medications, smoke fewer than 2 cigarettes per day and drink fewer than 2 alcoholic drinks per day. Participation involves four visits over a 3-year period, blood test, bone density test, urine test and cognitive testing. Compensation is provided. Call 435-7926 or 594-3839.

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