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Anticipates Depression Screening Day, Oct. 9
NIMH's Manji To Discuss Mood Disorders Research on Oct. 2

By Sophia Glezos Voit

With depression as the second leading cause of disability worldwide, says Dr. Husseini Manji, chief, Laboratory of Molecular Pathophysiology, NIMH, "It's just as important to know about the symptoms and treatments of mood disorders as those of cardiovascular disease and cancer."

Manji — who will address NIH staff at a noontime lecture Thursday, Oct. 2 in the Clinical Center on the latest mood disorders research emerging from the institute's intramural and extramural programs — has become as committed to spreading the hopeful but cautionary word about mood disorders as he's long been to researching how to treat them.

"Since we're dealing with frequently disabling and potentially devastating disorders, it makes no sense to know little or nothing about their signs and especially their treatability," Manji says. "Obviously, getting the scientific information and anti-stigma message out of the lab is just as critical as the research itself."

Current treatments are very effective, Manji says, but that's not to say that symptoms of depression or bipolar disorder are as easily resolved as the common sore throat. "The pathophysiology of depression is considerably more complicated than a bacterial infection," he says, "but treatments work, and not only do they return a better quality of life to people who've been suffering, but new research shows they're also cell-protective, which may translate into major long-term benefits."

The Oct. 2 lecture, to be held from noon to 1:30 p.m. in Lipsett Amphitheater, will also be broadcast live at, as well as archived on that site. The presentation is sponsored by NIMH and the NIH Work/Life Center, which are also organizing NIH Depression Screening Day a week later, on Oct. 9, from 10 a.m. to 3 p.m. at several sites on campus, elsewhere in Bethesda, in Rockville and in Frederick. The exact locations will be announced at a later time.

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