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Nobel Laureate Prusiner To Give Mahoney Lecture

Nobel laureate Stanley Prusiner will present the Florence Mahoney Lecture on Aging at 3 p.m., Wednesday, Oct. 14 in Masur Auditorium, Bldg. 10. His talk is sponsored by the National Institute on Aging and is part of the NIH Director's Wednesday Afternoon Lecture Series.

Dr. Stanley Prusiner

Prusiner, a professor of neurology at the University of California, San Francisco, will discuss "Prion Biology and Diseases: A Saga of Skeptical Scientists, Mad Cows, and Laughing Cannibals." His 1997 Nobel Prize in physiology or medicine was awarded for his unprecedented discovery of a new genre of disease-causing agents called prions. Prions, which appear to be infectious proteins, are implicated in a class of neurodegenerative diseases, the transmissible spongiform encephalopathies. These include kuru and Creutzfeldt-Jakob disease in humans, scrapie in sheep, and bovine spongiform encephalopathy (mad cow disease) in cows.

Prusiner has created a new field of research that has resulted in new concepts in the understanding of degenerative diseases of the central nervous system. These results have profound implications for future biomedical research in many areas of investigation.

Editor of 8 books and author of more than 200 articles, Prusiner received his undergraduate and medical training at the University of Pennsylvania and his postgraduate clinical training at the University of California, San Francisco. From 1969-72, he served in the Public Health Service at NIH.

A reception for him will follow the question and answer portion of his lecture. For accommodation and information, call Hilda Madine at 594-5595.

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