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Malaria Vaccine Study Needs Volunteers

Healthy men and women ages 18-45, without previous history of malaria or receipt of a malaria vaccine, are needed to participate in a study on the safety and effectiveness of a new investigational malaria vaccine at Walter Reed Army Institute of Research in Silver Spring. Health screening and financial compensation provided. Call 1-866-856-3259 toll free or (301) 319-9335/9320, or visit www.wrairclinicaltrials.com.

Metabolic Study for African-Americans

Healthy volunteers are needed for a study that is investigating the relationship of obesity to resting energy expenditure (REE) and fatty acid flux in healthy African Americans, ages 18 to 49 years. The study involves a 2-week period (excluding weekends) of outpatient visits to the Clinical Center for breakfast, weight measurement and to pick up meals. All meals will be provided during the study. Participation involves blood draws and metabolic testing. The last 2 days will require a 2-night inpatient stay. Compensation provided. Call (301) 402-7119 for information. Refer to protocol 04-DK-0061.

Depression Study Needs Volunteers

If you currently experience symptoms of depression, you may be eligible to participate in a research study. Symptoms include sadness, losing interest in your activities and changes in eating and sleeping patterns. Interested volunteers, 18 years or older, may be eligible to participate. If you qualify, participation involves a 2-3-hour visit, including questionnaires. The study does not include treatment, but we provide referrals. You will be compensated for your time. For more information, call the Uniformed Services University, (301) 295-3241.

Are You a Woman Who Has Been Depressed?

NIMH is looking for female volunteers to participate in a study that examines the role of hormones in depression. Participants should have experienced depression in the past but not be currently depressed, be between ages 18-45, be medically healthy and not be taking any medications, including birth control pills. Study includes thorough evaluations and compensation. For more information call Linda Simpson-St. Clair, (301) 496-9576 (TTY 1-866-411-1010).

NIAID Seeks HIV+ Volunteers

HIV positive volunteers are needed for a phase I/II clinical trial testing the safety and effectiveness of a new interleukin-2 (IL-2) analogue called BAY 50-4798. This study will test whether BAY 50-4798 causes immunologic changes similar to conventional IL-2 but with milder side effects. Patients must be on HIV medications, have a viral load less than 10,000, CD4 count of at least 200, and not have had prior IL-2 therapy. Travel assistance may be provided. Call Jocelyn Voell, (301) 435-7913.

Weight and Insulin Study

The Uniformed Services University of the Health Sciences is conducting a study examining weight and stress responses to exercise in African American and Caucasian men and women between the ages of 18 and 45. Volunteers will be compensated for their participation. Call (301) 295-1371.

Neurocognitive Measures Study

The Uniformed Services University of the Health Sciences is conducting a study examining the relationship between computerized and traditional neurocognitive measures with healthy adult men and women ages 18-79. Participants will complete a brief interview and participate in a one-time testing session in Bethesda. Participants will be compensated for their time. Call Lt. John Ashburn, (301) 295-2501 or email jashburn@usuhs. mil.

Heart Disease Risk Factors Study Recruits African Americans

Healthy volunteers are needed for a study investigating the relationship of obesity to heart disease risk factors in healthy, non-diabetic African American men and pre-menopausal women between the ages of 18-50. Specifically, the study is looking at risk factors for triglyceride concentration and the triglyceride-related risk factors of unhealthy cholesterol (low-density lipoprotein), good cholesterol (high-density lipoprotein) and body fat distribution. There will be a series of four outpatient visits to the Clinical Center, in which participants will have body fat analyses, an electrocardiogram, blood tests including cholesterol profiles, an oral glucose tolerance test and an intravenous glucose tolerance test. Compensation provided. Call (301) 402-7119 for information. Refer to protocol 99-DK-0002.

HIV+ Volunteers Needed

HIV+ volunteers with CD4 T cells greater than 500 cells/mm3 and viral loads less than 50 copies/mL are needed for a treatment-interruption study. Participants may be eligible for this study if they have never received IL-2, have never had a CD4+ count under 200 cells/mm3, do not have any significant medical problems, and are willing to halt their antiretroviral medications with close supervision. Travel assistance may be provided. Call Rosanne Burke, (301) 435-7937.


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