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Vol. LVIII, No. 21
October 20, 2006

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‘Astute Clinician’ Lecture Addresses Cancer Immunotherapy

  Dr. Steven A. Rosenberg  
  Dr. Steven A. Rosenberg  

“Listening to Patients: Lessons Learned in the Development of Cancer Immunotherapy,” is the subject of the 2006 Astute Clinician Lecture, scheduled for Wednesday, Nov. 1 at 3 p.m. in Masur Auditorium, Bldg. 10. The speaker is Dr. Steven A. Rosenberg, chief of surgery, NCI, and a professor of surgery at the Uniformed Services University of the Health Sciences and at George Washington University School of Medicine and Health Sciences.

Rosenberg pioneered the development of immunotherapy that resulted in the first effective immunotherapies for selected patients with advanced cancer. He also pioneered gene therapy and was the first to successfully insert foreign genes into humans and to conduct clinical studies of gene therapy for cancer. His studies of cell transfer therapies resulted in cancer regressions in patients with clonal repopulation of lymphocytes with anti-tumor reactivity. More recently he and his group have genetically engineered normal lymphocytes using genes encoding anti-tumor T cell receptors and demonstrated that these modified cells could mediate cancer regression in patients, the first effective gene therapy for cancer.

Rosenberg is the author of over 820 articles in the scientific literature covering various aspects of cancer research and has authored 8 books. A study published by the Institute for Scientific Information in May 1999 revealed that he was the most cited clinician in the world in the field of oncology for the 17 years from 1981 to 1998.

The Astute Clinician Lecture was established through a gift from the late Dr. Robert W. Miller and his wife, Haruko. It honors a U.S. scientist who has observed an unusual clinical occurrence, and by investigating it, has opened an important new avenue of research. The lecture is an NIH Director’s Wednesday Afternoon Lecture Series event. For information and accommodation, contact Sandeep Nair, (301) 496-1921. NIH Record Icon

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