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Vol. LXI, No. 18
September 4, 2009

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Karin To Speak on Inflammation and Metastasis, Sept. 15

Dr. Michael Karin
Dr. Michael Karin of the University of California, San Diego.

On Tuesday, Sept. 15 at 12:30 p.m., Dr. Michael Karin of the University of California, San Diego, will speak on “Control of Tumor Promotion and Metastatic Progression by Inflammatory Signaling,” in Lipsett Amphitheater, Bldg. 10. His talk is part of NIDCR’s seminar series “From Basic Research to Therapy—The Latest Frontier.”

Karin will describe his recent work on the role of inflammatory processes in the development of tumor metastasis. His research in prostate and lung cancer models supports the hypothesis that metastasis is driven not only by genetic alterations in cancer cells, as previously thought, but is also highly dependent on dynamic and reciprocal interactions between cancer cells and inflammatory cells. Inflammatory cells are recruited into tumors to produce pro-metastatic cytokines, which activate critical signaling pathways required for metastasis.

Karin is a leading authority on signal transduction pathways that regulate gene expression in response to extracellular stimuli. He is professor of pharmacology at the School of Medicine, UC San Diego, where he has been on the faculty since 1987. He is also the Frank and Else Schilling-American Cancer Society research professor and a member of the National Academy of Sciences. He has published more than 200 articles and is an inventor on many patents. Karin’s publications are among the most cited in the world.

If you wish to meet with Karin during his visit, contact Dr. Nadya Lumelsky at (301) 594-7703 or

Sign language interpretation will be provided. For more information, or for reasonable accommodation, contact Mary Daum, (301) 594-7559, and/or the Federal Relay (1-800-877-8339). NIHRecord Icon

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