Dr. David M. Knipe will deliver NIAID’s third annual Stephen E. Straus Memorial Lecture on Infectious Diseases. Knipe’s talk, “Continuing Challenges
in the Development
of a Herpes Vaccine: One Step Forward and Two Steps Backward,”
will take place on Friday, Dec. 10, at 1 p.m. in Lipsett Amphitheater, Bldg. 10.
Knipe is based at Harvard Medical School, where he is the Higgins professor and vice-chair of the department of microbiology and molecular
genetics and chair of the Harvard Program in Virology. His research focuses on herpes simplex
virus 2 (HSV-2), which causes genital herpes
and severe herpes infections in newborns and immunocompromised patients. Specifically,
he studies the molecular and cellular biology
of the virus, productive and latent infection and the mechanism of host immune response to HSV. Much of this work is geared toward developing
an HSV-2 vaccine.
Knipe will discuss ongoing research in his laboratory
as well as past and future attempts to develop an HSV-2 vaccine. He will also talk about the disappointing results from a recently
concluded phase III international trial of an HSV-2 vaccine and implications for the future of HSV-2 vaccine research.
Knipe earned his Ph.D. in cell biology from the Massachusetts Institute of Technology in 1976.
The lecture series honors Dr. Stephen Straus, who served NIAID for 30 years as a lab chief and senior investigator, continuing in this latter role even after his appointment as the first director of NCCAM.
NCCAM further honors Straus by holding its second annual Stephen E. Straus Distinguished Lecture in the Science of Complementary and Alternative Medicine on Wednesday, Dec. 15. Harvard’s Dr. Vikas Sukhatme will present “Promise for the Future in Yesterday’s Remedies:
Traditional Therapies to Modern Medicine” at 9 a.m. in Lipsett Amphitheater, Bldg. 10. All are invited to attend.