Overweight Volunteers Needed
NICHD is looking for men and women ages 35-70 who are overweight and have abnormal glucose levels. After an initial screening visit for general health assessment, participants will undergo treatment with a cortisol-blocking medication (mifepristone) or a non-active pill (placebo) for 7 days. Each participant will take both study agents with a gap of 6 to 8 weeks between the two. Testing before and after treatment with the study medications will include blood drawing over 24 hours, urine collection, an oral and an intravenous glucose tolerance test and 1- to 2-day overnight inpatient stay. Compensation will be provided. For more information, call 1-800-411-1222 (TTY 1-866-411-1010) and refer to study 11-CH-0208.
Reproductive Disorders Research Study
Research study on reproductive disorders in patients with early (precocious) puberty or age 14 and older with delayed or absent pubertal development and/or low levels of testosterone or estrogen. This study seeks to learn how gonadotropin-releasing hormone (GnRH) controls puberty and fertility. This research will study the range of abnormalities in GnRH-secretion disorders and how they are inherited. Call 1-866-444-2214 (TTY 1-866-411-1010). Se habla español. Refer to studies 12-CH-0049 and 12-CH-0050.
Pioglitazone Severe Asthma Clinical Trial
Patients with severe asthma may be eligible to participate in a study at the Clinical Center. The purpose of this study is to determine if a widely used agent for diabetes can improve asthma. Eligible patients will receive a comprehensive evaluation. There is no cost for participating in the study. For more information, contact our research coordinator, toll free, at 1-877-NIH-LUNG (1-877-644-5864), ext. 2 or via email at LungStudy@nhlbi.nih.gov. You may also contact the NIH Patient Recruitment and Public Liaison Office via TTY 1-866-411-1010.
Do You Have Asthma?
Participate in a study at NIH. Call 1-800-411-1222 (TTY 1-866-411-1010). Se habla español. Compensation will be provided.