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Vol. LXVI, No. 20
September 26, 2014

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Schadt To Give Mahoney Lecture, Oct. 1

Dr. Eric Schadt will discuss “A Multiscale Biology Approach for Dissecting the Complex Processes Underlying Aging and Aging-Related Phenotypes” Oct. 1 at 3 p.m. in Masur Auditorium, Bldg. 10. His presentation is the annual Florence Mahoney Lecture on Aging, sponsored by NIA, and part of the NIH Director’s Wednesday Afternoon Lecture Series.

Dr. Eric Schadt

Dr. Eric Schadt

Schadt is an expert on the generation and integration of very large-scale sequence variation, molecular profiling and clinical data in disease populations for constructing molecular networks that define disease states and link molecular biology to physiology. He has called for a shift in molecular biology toward a network-oriented view of living systems to complement reductionist, single-gene approaches that currently dominate biology. Such an approach, he says, would more accurately model the complexity of biological systems.

Schadt will focus on integration of the digital universe of information to better diagnose, treat and prevent human disease. His team at the Icahn Institute seeks to understand the vast network of genes, proteins, metabolites and environmental factors that drive the function of the human body.

Since 2011, Schadt has been director of the Icahn Institute for Genomics and Multiscale Biology, chair of the department of genetics and genomics sciences and Jean C. and James W. Crystal professor of genomics at Icahn School of Medicine at Mount Sinai, New York. He was previously chief scientific officer at Pacific Biosciences after serving as executive scientific director of genetics at Rosetta Inpharmatics, a subsidiary of Merck & Co. Schadt also was a senior research scientist at Roche Bioscience.

He received his B.A. in applied mathematics and computer science from California Polytechnic State University, his M.A. in pure mathematics from the University of California, Davis, and his Ph.D. in bio-mathematics from the University of California, Los Angeles. Thomson Reuters recently named Schadt among the “World’s Most Influential Scientific Minds 2014,” based on its analysis of the impact of his publications.

The annual Mahoney Lecture honors Florence Stephenson Mahoney (1899–2002), who devoted the last half of her life to successfully advocating for the creation of NIA and increased support for NIH.

There will be a reception and an opportunity to talk with the speaker in the NIH Library following the lecture.

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