The 2015 Excellence in Molecular Diagnostics lecture series speaker is Dr. Brian J. Reid, member of the Fred Hutchinson Cancer Research Center and professor of medicine. The title of his talk—to be given on Thursday, May 7 from 10 to 11:30 a.m. in Lipsett Amphitheater, Bldg. 10—is “Thinking Like a Cancer: Neoplastic Evolution in Time and Space.”
The lecture series, sponsored by NCI’s Division of Cancer Prevention, recognizes outstanding leaders who are making groundbreaking contributions in molecular diagnostics and who have demonstrated broad and integrated approaches in the development and implementation of diagnostics commensurate with emerging technologies.
Current attempts to reduce the morbidity and mortality of cancer by early detection, prevention and therapy have been thwarted by overdiagnosis of indolent conditions, “underdiagnosis” of life-threatening early disease and evolution of resistance to therapeutic interventions. This seminar will focus on neoplastic evolution in time and space in a cohort of patients with Barrett’s esophagus. They were followed for up to two decades to development of esophageal adenocarcinoma with a control population that did not progress. Strategies to decrease overdiagnosis and improve accurate identification of patients at risk for evolution to cancer as well as to evaluate possible pathways for development of resistance to therapy will be discussed.
For details contact Felicia Evans Long at Felicia.EvansLong@nih.gov.