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March 25, 2016
Briefs

Kinzler To Give Next Lecture in NCI Series, Apr. 4

Dr. Kenneth Kinzler will be the next speaker in the 4th annual NCI Excellence in Molecular Diagnostics Lecture Series on Monday, Apr. 4 from 10 to 11 a.m. in Lipsett Amphitheater, Bldg. 10. He will discuss “The Cancer Genome as a Clinical Biomarker.”

Dr. Kenneth Kinzler

Kinzler is a professor of oncology at Johns Hopkins University School of Medicine, co-director of the Ludwig Center at JHU and associate director for basic research for the Sidney Kimmel Comprehensive Cancer Center. He has produced classic studies of the genes causing human cancer, including the discovery of APC, the gene that initiates virtually all colorectal tumors. He is also known for his development of genetic methods for analyzing gene expression and mutations in human cancer leading to his most recent work on defining the cancer genome for more than a dozen human tumor types.

Kinzler has coauthored more than 375 peer-reviewed articles on the molecular analyses of cancer and holds over 125 patents. He is a member of the National Academy of Medicine, the National Academy of Inventors and is a fellow of the American Association of Cancer Research Academy.

Kinzler will discuss the potential of tumor DNA as a clinical biomarker. In particular, the technical and clinical aspects of using cancer-specific somatic mutations to detect low levels of tumor DNA released into blood and other clinical samples will be described. Examples of clinical utility that will be highlighted include screening, liquid biopsies, resistance monitoring and prognosis.

The lecture series, sponsored by the NCI Division of Cancer Prevention, recognizes outstanding leaders who are making groundbreaking contributions in molecular diagnostics and who have demonstrated integrated approaches in the development of diagnostics.

For more information, contact Felicia Evans Long, (240) 276-5076 or evanslongf@mail.nih.gov.

NIH Medical Arts is hosting an art exhibition featuring the work of Linda Brown, a designer and creative director with NIH Medical Arts for 48 years who died last fall. The retrospective show includes original silk screen posters created over a span of more than 4 decades, beginning with Brown’s first work in 1966. All are welcome to celebrate Brown’s life and work at the show opening on Thursday, Apr. 14 from 4 to 6 p.m. in the 5SE (southeast) corridor of the Clinical Research Center. Take the elevators from the parking information desk up to floor 5 and follow signs to 5SE. The show will be open from Apr. 1 to Sept. 30.
Exhibit Honors Medical Arts’ Brown

NIH Medical Arts is hosting an art exhibition featuring the work of Linda Brown, a designer and creative director with NIH Medical Arts for 48 years who died last fall. The retrospective show includes original silk screen posters created over a span of more than 4 decades, beginning with Brown’s first work in 1966. All are welcome to celebrate Brown’s life and work at the show opening on Thursday, Apr. 14 from 4 to 6 p.m. in the 5SE (southeast) corridor of the Clinical Research Center. Take the elevators from the parking information desk up to floor 5 and follow signs to 5SE. The show will be open from Apr. 1 to Sept. 30.

Postbaccalaureate Poster Day Planned, Apr. 20

Postbac Poster Day is scheduled for Wednesday, Apr. 20 at the Natcher Conference Center from 10 a.m. to 3:30 p.m. The keynote address will begin at noon and will be followed by presentation of Postbac Distinguished Mentoring Award(s) to NIH investigators selected by the postbacs. Poster session I will take place from 10 a.m. to noon and poster session II is from 1:30 to 3:30 pm.

Poster Day provides an opportunity for postbacs to share the research they have been conducting at NIH and at the same time develop scientific communication and networking skills. Posters will be reviewed by teams composed of graduate students, postdocs and staff scientists/clinicians. The authors of the top 20 percent will receive a letter acknowledging their accomplishments.

Investigators, staff scientists and scientific administrators can make a particularly important contribution to the event by visiting posters and engaging their authors in discussion. For more information, visit https://www.training.nih.gov/postbac_poster_day.

Next Protocol Navigation Lecture, Apr. 4

The IRP Protocol Navigation Training Program Seminar Series continues with a lecture to be held Monday, Apr. 4 from 2 to 3 p.m. in Bldg. 50, Conf. Rm. 1227/1328. The program is a trans-NIH effort to develop resources and tools and to provide training for intramural staff and contractors involved in protocol development, writing, coordination and management. Dr. Sara Chandros Hull, chair of the NHGRI IRB and director of the NHGRI bioethics core, will present “On Becoming the Central IRB of Record for a Multi-Site Study: Opportunities, Challenges and Lessons Learned.” For more information, contact Marcia Vital, (301) 451-9437, vitalm@mail.nih.gov.

‘MEDIATION ANALYSIS’
MacKinnon To Give Next ‘Mind the Gap’ Seminar, Apr. 8

Dr. David P. MacKinnon

Dr. David P. MacKinnon, Foundation professor, department of psychology, Arizona State University, will present on the topic “Applying Mediation Analysis to Understand How Interventions Work” at the next Medicine: Mind the Gap seminar. The event is scheduled for Friday, Apr. 8 from 11 a.m. to noon via NIH Videocast, http://videocast.nih.gov/.

MacKinnon will describe mediation analysis methods with attention to solutions for some of the limitations of these methods. He has been developing, evaluating and applying methods to assess how interventions work for 30 years. He received the Merit Research in Time Award from the National Institute on Drug Abuse for his research on mediation analysis. He was a consulting editor of the journal Prevention Science and is on the editorial board of Psychological Methods. MacKinnon has been a principal investigator on several NIH grants.

He will accept questions before and during his presentation via email at prevention@mail.nih.gov and on Twitter with #NIHMtG.

Register for the event at https://prevention.nih.gov/programs-events/medicine-mind-the-gap.

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