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July 1, 2016
Milestones

Holland Named NIAID Scientific Director

Dr. Steven Holland
Dr. Steven Holland

Dr. Steven M. Holland has been appointed director of the NIAID Division of Intramural Research, succeeding Dr. Kathy Zoon. Holland has served NIAID as chief of the Laboratory of Clinical Infectious Diseases since 2004 and as NIH deputy director for intramural clinical research since 2011. His research areas of special interest have included Job’s syndrome (autosomal dominant STAT3 deficiency) and the genetic conditions predisposing people to mycobacterial infections.

More recently, Holland has been interested in genetic conditions associated with severe coccidioidomycosis and acquired forms of anticytokine autoimmunity predisposing to opportunistic infections. He is the author of more than 500 publications and has been named an NIH distinguished investigator.

Holland has received the American College of Physicians Award for Science, the Boyle Scientific Achievement Award of the Immune Deficiency Foundation, the American Society for Microbiology Abbott Award, the Erwin Neter Award of the Association of Medical Laboratory Immunologists and the NIH Distinguished Clinical Teacher Award, among other honors.

Holland received his B.A. from St. John’s College in Annapolis in 1979 and his M.D. from Johns Hopkins University School of Medicine in 1983. He remained at Johns Hopkins for his internal medicine residency, chief residency and fellowship in infectious diseases. During that time he worked with Dr. Thomas Quinn on chlamydia diagnosis and pathogenesis. Holland came to NIAID in 1989 as a National Research Council fellow in Dr. Sundararajan Venkatesan’s section in the Laboratory of Molecular Microbiology, working on rev-mediated transcriptional regulation of HIV.

Shifting his research to the host side, with a focus on phagocyte defects and their associated infections, Holland joined Dr. John Gallin’s section in the Laboratory of Host Defenses (LHD) in 1991. Holland’s work in LHD centered on the pathogenesis and management of chronic granulomatous disease, as well as other congenital immune defects affecting phagocytes. He was tenured in 2000 and became chief of the immunopathogenesis section, which now resides within LCID.

“Dr. Holland is a highly skilled and dedicated physician-scientist and administrator, and I am very pleased that he has agreed to take on this vitally important role within the institute,” said NIAID director Dr. Anthony Fauci, announcing the appointment. “I would also like to express my appreciation to NIAID principal deputy director Dr. Hugh Auchincloss, who has served so capably as acting director of DIR since Dr. Zoon stepped down last year.”

Dr. Robert Munford will serve as acting chief of the LCID, pending recruitment of a permanent successor to Holland, who will continue to serve as chief of the immunopathogenesis section within the LCID.

Boerboom Heads CSR Division

Dr. Lawrence Boerboom
Dr. Lawrence Boerboom

Dr. Lawrence Boerboom is the new director of the Division of Physiological and Pathological Sciences at the Center for Scientific Review. He has been chief of CSR’s cardiovascular and respiratory sciences integrated review group since 2009.

“We are pleased that Dr. Boerboom has agreed to step into this important position,” said CSR director Dr. Richard Nakamura. “He has excelled as a leader in academia, business and CSR, and he will bring a wealth of management and scientific expertise to the job…Throughout his career, Dr. Boerboom has successfully built bridges between basic and clinical researchers and cultivated a deep appreciation for multidisciplinary research.”

The Division of Physiological and Pathological Sciences coordinates reviews of NIH grant applications in four integrated review groups—digestive, kidney and urological systems; endocrinology, metabolism, nutrition and reproductive sciences; infectious diseases and microbiology; and immunology—that include 44 standing review panels managed by an equal number of scientific review officers.

Boerboom came to CSR in 2004 as an SRO for a study section that reviews cardiac- and vascular-related small business grant applications.

Prior to joining CSR, he was director of research at LifeCell Corp. in Branchburg, N.J., where he led a team developing tissue-engineered medical devices. He earlier had a 20-year career on the faculty of the Medical College of Wisconsin, holding a primary appointment in cardiothoracic surgery and a secondary appointment in physiology.

Boerboom also served as director of cardiovascular surgical research. His research focused on factors influencing myocardial blood flow, cardiac function and vascular bypass graft atherosclerosis. He earned his Ph.D. in physiology from the University of North Dakota.

Long Appointed Director of NIGMS Division

Dr. Rochelle Long
Dr. Rochelle Long

Dr. Rochelle Long is the new director of the NIGMS Division of Pharmacology, Physiology, and Biological Chemistry (PPBC). A pharmacologist, she has played leading roles in fostering research in pharmacogenomics through national and international collaborations.

The division is broad in scope, funding research from basic studies in synthetic chemistry, enzymology, biotechnology, chemical biology and the glycosciences to clinical areas that include pharmacology, anesthesia, sepsis, traumatic injury and wound healing.

“Dr. Long’s skills are ideal for directing this wide-ranging division,” said NIGMS director Dr. Jon Lorsch. “She not only has a true passion for the science, she is also a proven leader who excels at promoting collaborations, facilitating communication and inspiring people.”

Long joined NIGMS in 1990 as a program director in PPBC and became chief of the division’s Pharmacological and Physiological Sciences Branch in 1998. She has served as acting director of PPBC since May 2015.

Long was instrumental in establishing and overseeing the trans-NIH Pharmacogenomics Research Network (PGRN), a nationwide team of scientists focused on understanding genetic contributions to individual drug response. She was also a catalyst for forming multiple PGRN partnerships, including the Global Alliance for Pharmacogenomics, a collaboration with the RIKEN Center for Genomic Medicine in Japan, and the Clinical Pharmacogenetics Implementation Consortium, an authority on using genetic information in medicine.

Her honors include awards from the Office of the NIH Director for creating and leading the PGRN, organizing an NIH-FDA workshop on adverse drug reactions and coordinating a meeting and report on oral drug bioavailability with NIH, FDA and pharmaceutical industry participants.

Long received a B.S. in chemistry from Bucknell University then worked at the Chemical Industry Institute of Toxicology (now called the Hamner Institutes for Health Sciences) in Research Triangle Park, N.C. She returned to school to earn a Ph.D. in pharmacology from the Uniformed Services University of the Health Sciences.

She conducted postdoctoral research in NHLBI’s Laboratory of Chemical Pharmacology through what was then the NIGMS Pharmacology Research Associate program, which she later co-directed. Prior to joining NIGMS, she served as a faculty member at the University of Maryland, Baltimore’s School of Pharmacy.

“I care deeply about NIGMS and look forward to leading the PPBC division,” said Long. “There are tremendous opportunities to build bridges across the scientific disciplines at the institute and NIH, and I want to work with colleagues and the broader scientific community to strengthen emerging fields and promote the cross-disciplinary research of the future.”

NIH’ers Support Peace Officers’ Memorial Service

NIH’ers are among PHS Commissioned Corps officers who supported the annual service honoring fallen law enforcement officials.
NIH’ers are among PHS Commissioned Corps officers who supported the annual service honoring fallen law enforcement officials.

PHOTO: MARC GLUCKSMAN

May 15th marked the 35th annual National Peace Officers’ Memorial Service, which occurs during Police Week. The service commemorates law enforcement officials who have died in the line of duty the previous year.

As is customary, police officers and the fallen officers’ family members from throughout the U.S. and internationally came to pay their respects. The keynote speaker this year was Sally Quillian Yates, deputy U.S. attorney general.

For a majority of those at the service, it’s a time of reflection and honoring heroes. During the event, however, a few guests sought medical care for injuries ranging from mild to severe. Anticipating this need, the Office of the Attending Physician to Congress and the U.S. Capitol Police had requested that the Department of Health and Human Services provide health care support.

To prepare for an event of this size and scope, the officers volunteered for 2 days to train for emergencies large or small. Those deployed for the service included National Disaster Medical System personnel and Commissioned Corps officers, including several from NIH. Multiple medical support teams provided health care and medical and logistical assistance.

Brown Joins NIGMS as Program Director

Dr. Patrick Brown
Dr. Patrick Brown

Dr. Patrick Brown recently joined NIGMS as a program director in the Undergraduate and Predoctoral Training Branch in the Division of Training, Workforce Development, and Diversity. In this position, he administers diversity-focused institutional research training grants, individual fellowships and administrative supplements. Before joining NIGMS, Brown was a chemistry teacher at Watkins Mill High School. He has prior NIH experience, having served as chief of the quantitative methods for macromolecular interactions unit and also as a research fellow in the Laboratory of Biomedical Engineering and Physical Science, both at NIBIB. Brown earned a Ph.D. in biochemistry from the University of Maryland and was a postdoctoral research fellow at the former University of Maryland Biotechnology Institute. He also served in the U.S. Army as a mortar gunner at Ft. Lewis, Wash., and later in the Army National Guard as a light infantry squad leader in Greenfield, Mass.

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