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November 17, 2017
Milestones
After 20 Years, Edmonds Retires from NIGMS
Dr. Charles G. Edmonds

Dr. Charles G. Edmonds retired from his position as program director in NIGMS’s Division of Cell Biology and Biophysics recently, putting a cap on a remarkable globe-trotting, highly interdisciplinary career.

At NIH and beyond, Edmonds is well-regarded for his scientific and administrative contributions in biochemical analysis and structural biology. He is a card-carrying mass spectrometrist and an enthusiastic supporter of what he calls “gizmotronics,” the development of new instruments, methods and technologies to solve biological problems.

Edmonds grew up in the Midwest and received his B.S. from the University of Missouri. Military service as a medical laboratory specialist interrupted his graduate studies, but following his service, Edmonds resumed graduate work in Glasgow, Scotland. There, he developed study methods for human steroids and sterol natural products; met his wife, Valerie; and took up the sport of climbing.

He returned to the U.S. to postdoctoral work in geochemistry and renewable energy at UC Berkeley. He then studied natural products from Amazonian plants and animals as an employee of the National Research Council of Brazil. Later, during a second postdoc at the University of Utah, he contributed to the discovery of novel modified nucleotides in transfer RNAs and the development of new methods of mass spectrometry analysis, while pursuing skiing and mountaineering.

Before joining NIH in 1997, Edmonds was a program director with the office of biological and medical research at the Department of Energy and, prior to that, a senior staff scientist at Battelle Pacific Northwest National Laboratory, where he studied how radiation and chemical damage can modify nucleic acids and proteins in cells.

Edmonds played a significant role in the NIGMS program of structural genomics and other trans-NIH initiatives. He was responsible for overseeing the NIGMS (joint with NCI) investment in the GM/CA synchrotron beamline for structural biology at Argonne National Laboratory, which has become one of the most valuable resources for X-ray diffraction studies of molecular structure.

Edmonds frequently organized workshops to share knowledge of the enabling technologies for protein production, crystallization and structure determination. He handled a large portfolio of research grants and showed exceptional initiative in utilizing the SBIR/STTR grant mechanisms to promote innovative science.

Among the many things Edmonds said he will miss about working at NIH is his “ringside seat for world-class science.” He added, “I will also miss my opportunity to interact with the physicians, scientists and engineers supported by NIGMS. I admire and envy them (mostly) and get a vicarious reward from their success.”

While at NIGMS, Edmonds pursued his interest in public health, obtained a graduate certificate therein and served on details to Kenya and to the public health laboratory division in the D.C. department of forensic sciences. “I understand and endorse the argument that basic science is necessary to eventually have something to translate into improved diagnosis, treatment and prevention of disease, but I have admired and envied my colleagues in the categorical institutes and elsewhere who are on or near the field of battle,” said Edmonds.

“Charles has had an exceptionally interesting life, full of adventure and challenge,” said Dr. Peter Preusch, acting director of the Cell Biology and Biophysics Division, NIGMS. “He has been a terrific colleague and friend who will be difficult to replace.”

Edmonds is known for a wry wit that reflects his time in the U.K. and his classical education. His colleagues at NIGMS and throughout NIH will miss him. In recent years, he has taken up sailing. Colleagues wish him well as he and Valerie sail off into retirement together.

NCIís Srivastava Wins Proteomics Award

Dr. Sudhir Srivastava
Dr. Sudhir Srivastava

Dr. Sudhir Srivastava, chief of the cancer biomarkers research group, NCI Division of Cancer Prevention, was honored by the Human Proteome Organization (HUPO) with the 2017 Clinical and Translational Proteomics Award Sept. 20 at the group’s annual World Congress in Dublin, Ireland.

The group named Srivastava “a visionary and proactive leader who has worked with HUPO since its inception.” They cited his “tremendous commitment and leadership” to the NCI Early Detection Research Network, which he has headed from its start in 2000, and which focuses on the discovery and validation of proteomics, genomic, metabolomics, epigenomic and other “omic” markers of cancer detection and prognosis.

In the field of proteomic biomarkers, translational research bridges the gap between basic research discoveries that identify biomolecules involved in or are the result of carcinogenesis and the clinical application of these discoveries.

Four Named to NIAMS Advisory Council

Four new members recently joined the National Arthritis and Musculoskeletal and Skin Diseases Advisory Council.

NIAMS director Dr. Stephen Katz (c) and deputy director Dr. Robert Carter (r) welcome new members to the institute’s council. They are (from l) Dr. Michael Yaszemski, Dr. Judith James, Rosemary Markoff and Dr. Michael Econs.
NIAMS director Dr. Stephen Katz (c) and deputy director Dr. Robert Carter (r) welcome new members to the institute’s council. They are (from l) Dr. Michael Yaszemski, Dr. Judith James, Rosemary Markoff and Dr. Michael Econs.

Dr. Michael J. Econs is the Glenn W. Irwin, Jr. professor of endocrinology and metabolism and chief of the division of endocrinology and metabolism at Indiana University School of Medicine. His primary area of research is in the genetic aspects of metabolic bone diseases.

Dr. Judith A. James is vice president of clinical affairs and chair of the arthritis and clinical immunology research program at the Oklahoma Medical Research Foundation. Her research aims to understand the etiology and pathogenic mechanisms of systemic autoimmune, rheumatic diseases, with a special interest in minority groups.

Dr. Michael J. Yaszemski is professor of orthopaedics and bioengineering and director of the tissue engineering and biomaterials laboratory at the Mayo Clinic. His research focuses on the development of biodegradable scaffold polymers to support bone and spinal cord regeneration using tissue engineering strategies.

Rosemary J. Markoff began her career in accounting until a diagnosis of scleroderma led her down a path toward patient advocacy and disease awareness. She became actively involved in the Scleroderma Foundation and has served in numerous leadership roles over the last 15 years.

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