Study Seeks Healthy Older Adults

Healthy older adults, ages 55-70, are invited to participate in an outpatient research study investigating the benefits of tart cherry and aroniaberry supplementation on vascular health. The goal of the study is to determine whether the supplements improve blood flow and blood vessel function that can affect your heart. Eligible participants must be medication-free and in good general health. The study will be carried out in an outpatient clinic and includes 7 visits over 3-4 months. Compensation for the study is provided. For more information, call 1-800-411-1222 (TTY 1-866-411-1010) and refer to study 15-NR-0085 or visit www.clinicaltrials.gov.

People with Dry Mouth Needed

NIDCR is seeking people with dry mouth due to radiation therapy for head and neck cancer. Researchers are testing whether an investigational gene therapy using “AAv2hAQP1” increases saliva in patients who have received radiation therapy for head and neck cancer. Travel to and from the Clinical Center (within the U.S.) will be provided. For more information, call 1-866-444-2214 (TTY 1-866-411-1010). Read more online at https://go.usa.gov/x8yXE. Refer to study 15-D-0129.

Study on Depression, Repeated Doses Of Ketamine Now Enrolling

Join a research study on depression. The purpose of the study is to evaluate the rapid and sustained antidepressant effects of repeat doses of ketamine in the brain. We want to learn how ketamine affects areas of the brain important in regulating mood and if there are unique signatures that could help predict who may respond to the drug. Also, we want to see if repeated doses of ketamine are safe and effective in treating the symptoms of depression. We are enrolling eligible adults, ages 18 to 65 with major depressive disorder. This inpatient study lasts 14-20 weeks. Procedures include a medication taper and drug-free period, taking repeated doses of the research drug, taking placebo, multiple brain imaging scans, transcranial magnetic stimulation and psychological testing. After completing the study, participants receive short-term follow-up care at NIH while transitioning back to a provider. There is no cost to participate. Compensation is provided. Study enrolls eligible participants from across the U.S. Travel arrangements are provided. Costs are covered by NIMH. To find out if you qualify, call 1-877-646-3644 (1-877-MIND-NIH) TTY 1-866-411-1010. Refer to study 17-M-0060.