
On the Cover
Molecular view of DHHC palmitoyltransferases. Human DHHC20 (yellow) is embedded in the Golgi membrane (green), a compartment located inside cells. DHHC20 attaches a fatty acid chain (white) to a target protein (blue, foreground), which anchors the protein to the Golgi membrane. NIH researchers have reported the first 3D structure of DHHC enzymes. The finding promises to improve drug design for common forms of cancer.
Jeremy Swan/NICHD