A woman with HIV who received a cord blood stem cell transplant to treat acute myeloid leukemia has had no detectable levels of HIV for 14 months despite cessation of antiretroviral therapy (ART). The woman is the third known case of HIV remission following a stem cell transplant.
Using an experimental drug, researchers suppressed a mutated amyotrophic lateral sclerosis (ALS) gene. Studies in mice demonstrate the therapy shows potential in treating rare, aggressive forms of ALS caused by mutations in the fused in sarcoma (FUS) gene.
Survey data found that supportive relationships with family and friends and healthy behaviors—such as engaging in physical activity and better sleep—appeared to shield against the harmful effects of the pandemic on adolescents’ mental health.
An NIH clinical trial found that giving peanut oral immunotherapy to highly peanut-allergic children ages 1 to 3 safely desensitized most of them to peanut and induced remission of peanut allergy in one-fifth.
A small NICHD-led study showed that a SARS-CoV-2 infection during pregnancy may cause inflammatory immune responses in the fetus, even if the virus does not infect the placenta.
The survival rate of extremely preterm infants born from 2013 through 2018 in a large network of U.S. research centers improved to 78.3 percent.
A study conducted in two rural Massachusetts jails found that people with opioid use disorder (OUD) who were incarcerated and received buprenorphine, a medication approved to treat OUD, were less likely to face re-arrest and reconviction after release.
A team led by NIAID’s Dr. Paolo Lusso developed and tested an mRNA HIV vaccine in animals. Study results were published in Nature Medicine.
The FDA recently approved a long-acting HIV prevention medication. Developed by ViiV Healthcare, cabotegravir is injected once every 2 months. FDA has approved the medicine for use by adults and adolescents weighing at least 77 pounds who are at risk of sexually acquiring HIV.
A small NIH-funded study has linked sleep-disordered breathing in early pregnancy with insulin resistance or difficulty clearing glucose from the blood. The results, which appear in Sleep, strengthen the link between sleep-disordered breathing, which includes pauses or slowing of breathing during sleep, and gestational diabetes.