NIH Record - National Institutes of Health

Offering Buprenorphine to Inmates Has Hopeful Results

A study conducted in two rural Massachusetts jails found that people with opioid use disorder (OUD) who were incarcerated and received buprenorphine, a medication approved to treat OUD, were less likely to face re-arrest and reconviction after release.

NIH Celebrates FDA Approval of Injectable Drug for HIV Prevention

The FDA recently approved a long-acting HIV prevention medication. Developed by ViiV Healthcare, cabotegravir is injected once every 2 months. FDA has approved the medicine for use by adults and adolescents weighing at least 77 pounds who are at risk of sexually acquiring HIV.

Sleep-Disordered Breathing in Early Pregnancy Linked to Diabetes Risk

A small NIH-funded study has linked sleep-disordered breathing in early pregnancy with insulin resistance or difficulty clearing glucose from the blood. The results, which appear in Sleep, strengthen the link between sleep-disordered breathing, which includes pauses or slowing of breathing during sleep, and gestational diabetes.

Viagra May Reduce Risk of Alzheimer’s Disease

NIA-funded researchers have found that people who took the drug sildenafil, sold under the brand names Viagra and Revatio, were less likely to develop Alzheimer’s disease (AD). Sildenafil also enhanced growth and reduced Alzheimer’s biomarkers in cultured human neurons.

SARS-CoV-2 Can Infect Inner Ear Cells

A commonly reported symptom of Covid-19 infection has been loss of taste and smell. NIAID-funded researchers have found another sensory connection: SARS-CoV-2 can infect inner ear cells.

Drug Combination Shows Promise for Children with APL

A clinical trial has found the combination of all-trans retinoic acid, which is a metabolite of vitamin A, and arsenic trioxide is highly effective in children with standard- and high-risk acute promyelocytic leukemia, or APL.

Targeted Antibiotic Shows Promise Against Lyme

Researchers found that a neglected antibiotic called hygromycin A selectively kills Borelliella burgdorferi, the bacteria that cause Lyme disease. The antibiotic was able to treat Lyme disease in mice without disrupting the microbiome.

The NIH Record

The NIH Record, founded in 1949, is the biweekly newsletter for employees of the National Institutes of Health.

Published 25 times each year, it comes out on payday Fridays.

Editor: Dana Talesnik
Dana.Talesnik@nih.gov(link sends email)

Assistant Editor: Eric Bock
Eric.Bock@nih.gov(link sends email)

Assistant Editor: Amber Snyder
Amber.Snyder@nih.gov(link sends email)