Versions of a gene linked to schizophrenia may trigger runaway pruning of the teenage brain’s still-maturing communications infrastructure, NIH-funded researchers have discovered.

NIH researchers have identified a striking signature in tumor DNA that occurs in 5 different types of cancer. They also found evidence that this methylation signature may be present in more types of cancer.

A criminal justice program that requires offenders convicted of alcohol-related offenses to stop drinking and submit to frequent alcohol testing with swift, certain and modest sanctions for a violation was linked to a significant reduction in county-level mortality rates in South Dakota.

An international team of nearly 100 researchers toiled for a decade and overcame tough technical challenges to decipher the genome of the blacklegged tick (Ixodes scapularis).

A clinical trial has begun testing an experimental stem cell treatment against the best available biologic therapies for severe forms of relapsing multiple sclerosis (MS). The trial, sponsored by NIAID, will compare the safety, efficacy and cost-effectiveness of the two approaches.

Tuberculosis (TB), an ancient disease, is the leading infectious cause of death globally, yet the world’s only licensed TB vaccine, bacille Calmette-Guérin (BCG), was developed a century ago.

Dietary supplements containing zinc and folic acid—marketed as a treatment for male infertility—do not appear to improve pregnancy rates, sperm counts or sperm function, according to a study by NICHD.

Nonmedical use of prescription opioids more than doubled among adults in the United States from 2001-2002 to 2012-2013, based on a study from NIAAA.

Researchers supported by NIH have developed a clinical-grade stem cell line, which has the potential to accelerate the advance of new medical applications and cell-based therapies for millions of people.

A subgroup of women with polycystic ovary syndrome (PCOS), a leading cause of infertility, may produce excess adrenal hormones, according to an early study by researchers at NICHD and other institutions.