Researchers have demonstrated that a drug originally targeted unsuccessfully to treat cancer may have new life as a potential treatment for Duchenne muscular dystrophy.
Research is essential to determining how best to screen pregnant women for opioid use disorder, to treat pregnant women who have the disorder and to care for infants as they experience withdrawal symptoms, according to experts.
Scientists have identified a rare genetic mutation that results in a markedly increased susceptibility to infection by human rhinoviruses (HRVs)—the main causes of the common cold.
Children born to women who had gestational diabetes and drank at least one artificially sweetened beverage per day during pregnancy were more likely to be overweight or obese at age 7, compared to children born to women who had gestational diabetes and drank water instead of artificially sweetened beverages, according to a study.
Researchers using a new method they developed have discovered a trove of neuronal subtypes and gene regulators. It allows for the discovery of subtypes based on their unique profiles of molecular switches that regulate gene expression within the cell.
A large, long-term study suggests that middle- aged Americans who have vascular health risk factors—including diabetes, high blood pressure and smoking—have a greater chance of suffering from dementia later in life.
A new study identifies genes that are necessary in cancer cells for immunotherapy to work, addressing the problem of why some tumors don’t respond to immunotherapy or respond initially but then stop as tumor cells develop resistance to immunotherapy.
An experimental drug appears to slow the progression of Niemann-Pick disease type C1 (NPC1), a fatal neurological disease, according to results of a clinical study led by researchers at NIH. The study appears in The Lancet.
A team of scientists led by NIH researchers has identified an enzyme that could help in the continuous battle against mid-life obesity and fitness loss. The discovery in mice could upend current notions about why people gain weight as they age and could one day lead to more effective weight-loss medications.
NIH-funded neuroscientists have created a 3-D window into the human brain’s budding executive hub assembling itself during a critical period in prenatal development. What’s more, they used it to discover and experimentally correct—in a petri dish—defective cell migration caused by an autism-related disorder.