NIH Record - National Institutes of Health

New Targets Revealed for Anti-Malaria Drugs

The deadliest malaria parasite needs two proteins to infect red blood cells and exit the cells after it multiplies, a finding that may provide researchers with potential new targets for drug development, according to researchers funded by NIH.

Study Shows How Memories Ripple Through the Brain

Using an innovative “NeuroGrid” technology, scientists showed that sleep boosts communication between two brain regions whose connection is critical for the formation of memories. The work was partially funded by the BRAIN Initiative.

Researchers Identify Genetic Variations Linked to Oxygen Drops During Sleep

Researchers have identified 57 genetic variations of a gene strongly associated with declines in blood oxygen levels during sleep. Low oxygen levels during sleep are a clinical indicator of the severity of sleep apnea, a disorder that increases the risk of heart disease, dementia and death.

Pathogenic Tau and Cognitive Impairment Are Precipitated by a High-Salt Diet

High levels of dietary salt can activate a pathway in the brain to cause cognitive impairment, according to a new study. The paper, which was published in Nature, shows that this effect is not due to a loss in blood flow to the brain as originally thought, but rather to clumps of a protein linked to several forms of dementia in humans.

The NIH Record

The NIH Record, founded in 1949, is the biweekly newsletter for employees of the National Institutes of Health.

Published 25 times each year, it comes out on payday Fridays.

Editor: Dana Talesnik
Dana.Talesnik@nih.gov

Assistant Editor: Eric Bock
Eric.Bock@nih.gov

Staff Writer: Amber Snyder
Amber.Snyder@nih.gov