BTK Study Seeks Volunteers

Pharmacologic therapy with Bruton’s tyrosine kinase (BTK) inhibitors is associated with an increased risk of heart problems like atrial fibrillation, bleeding and high blood pressure (hypertension), which can lead to sudden death. There is currently no standard for cardiac screening or monitoring patients on BTK inhibitors. Researchers at NHLBI are investigating the relationship between the development of heart problems in patients on BTKi as it relates to other variables. Participants do not pay for tests, treatments or procedures. Travel may be reimbursed. Contact the Clinical Center Office of Patient Recruitment at (866) 444-2214 (TTY users dial 711) or ccopr@nih.gov. Refer to study #000923-H. Online: https://bit.ly/414oewX.

Metastatic Thyroid Cancer Study Recruits Participants

The standard treatment for thyroid cancer is radioactive iodine (RAI). How much RAI goes into the cancer cells? During this study, doctors will assess a new imaging tool—124I PET/CT—to evaluate how much iodine goes into the tumor. This study aims to compare how much iodine goes into cancer cells after two different methods of stimulation of RAI uptake. Imaging will be followed by therapy with RAI dose individualized to each patient. The NIDDK research team is seeking adult patients, ages 18 and older, with thyroid cancer that has spread outside the thyroid to lymph nodes, lungs or bones. All tests and procedures are provided at no cost. Travel and lodging assistance may be provided. For more information and enrollment, contact the Clinical Center Office of Patient Recruitment at (866) 444-2214 (TTY users dial 711) or ccopr@nih.gov. Refer to study #19-DK- 0050. Online: https://bit.ly/3rvni46.

NHLBI Seeks Pregnant Women for Sickle Cell Study

A research study at NHLBI is looking for pregnant women between 18 and 45 years of age who are at risk of having an infant with sickle cell disease and women who are pregnant with no risk of having an infant with sickle cell to donate their baby’s cord blood. Tests and procedures provided at no cost. Travel may be reimbursed. Contact the Clinical Center Office of Patient Recruitment (866) 444-2214 (TTY users dial 711) or ccopr@nih.gov. Refer to study #01-H-0122. Online: https://go.usa.gov/xSQqW.

Adults with Aplastic Anemia Needed

NHLBI seeks adults with severe aplastic anemia (SAA) for a research study determining viability and safety of early initiation of oral therapy with cyclosporine and eltrombopag in people with SAA. Compensation will be provided. For details, call the Office of Patient Recruitment at (866) 444-2214 (TTY users dial 711). Refer to study 20-H-0033. Online: https://go.usa.gov/xwbDt.