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NIH Record - National Institutes of Health
Coronavirus spike protein structure

July 24, 2020

  • Dr. James C. Harris

    Harris Reflects on Decades of Research into Rare Disorder

    By Dana Talesnik

    Determined to improve outcomes for patients with severe developmental neuropsychiatric disorders, Dr. James C. Harris describes promising treatments, focusing on Lesch-Nyhan syndrome, in which patients are prone to self-injury. He spoke virtually at a recent Clinical Center Grand Rounds.
  • Fagerlin speaks on video.

    Fagerlin Discusses Economics and Value of Trust

    By Rich McManus

    Two lies work against a culture of trust in the workplace, said guest speaker Richard Fagerlin at a recent DDM Seminar: Trust is earned over time, and trust takes a lifetime to earn, but only a second to lose.

  • Medical History Matters in Era of Big Data

    By Eric Bock

    Scientists involved in machine learning often don’t know the origins of the datasets they use to write and test algorithms, including where the Pima Indians Diabetes Database (PIDD) came from, explained Dr. Joanna Radin at a recent virtual NLM history talk.
Coronavirus spike protein structure

On the Cover

Coronavirus spike protein structure. Coronaviruses are enveloped viruses responsible for 30 percent of mild respiratory infections and atypical deadly pneumonia in humans worldwide. These pneumonia include those caused by infections with SARS-CoV and MERS-CoV. The coronavirus spike glycoprotein mediates virus entry into cells and represents an important therapeutic target. The illustration shows a viral membrane decorated with spike glycoproteins; highlighted in red is a potential neutralization site, which is a protein sequence that might be used as a target for vaccines to combat coronaviruses.

Photo: DAVID VEESLER, UNIVERSITY OF WASHINGTON

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