When Covid struck, NHLBI’s Laboratory of Single Molecule Biophysics recently had witnessed significant milestones. They’d seen how solo topoisomerases might behave when faced with a chemotherapeutic drug. Could the team adapt their observations to potential Covid drugs?
The 7th annual BRAIN Initiative Investigators Meeting was packed with science talks covering the spectrum of neuroscience. Researchers shared scientific developments, explored possible new directions and identified areas for potential collaboration.
The opioid epidemic was swept off the front pages as media focus shifted to the Covid-19 pandemic, said U.S. surgeon general Dr. Vivek Murthy. “But the struggles have not disappeared,” he added during a virtual conversation with NIH director Dr. Francis Collins at the second annual HEAL Initiative investigator meeting.
On the Cover
New approach shows promise for treating cystic fibrosis. In people with cystic fibrosis, a protein that releases a key infection-fighting agent (red spheres), is missing or defective (brown ribbon). Amphotericin (white structure) can form channels to release bicarbonate, restoring the antibiotic properties of the airway surface liquid, which plays a key role in maintaining lung health.
Photo: Rebecca Schultz, Carle Illinois College of Medicine