NIH Record - National Institutes of Health

Scientists Discover New Molecular Pathway Shared by Two Neurodegenerative Disorders

Scientists from two independent research teams have discovered how the mislocalization of a protein, known as TDP-43, alters the genetic instructions for UNC13A, providing a possible therapeutic target that could have implications in treating amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD) and other forms of dementia.

The NIH Record

The NIH Record, founded in 1949, is the biweekly newsletter for employees of the National Institutes of Health.

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Assistant Editor: Eric Bock
Eric.Bock@nih.gov (link sends e-mail)

Staff Writer: Amber Snyder
Amber.Snyder@nih.gov (link sends e-mail)