Repurposed Drug Helps Obese Mice Lose Weight
An experiment in mice using disulfiram, which has been used to treat alcohol-use disorder for more than 50 years, normalized body weight and reversed metabolic damage in obese middle-age mice of both sexes.
Drug to Treat Alcohol Use Disorder Shows Promise Among Drinkers with High Stress
A new medication that targets part of the brain’s stress system may help reduce alcohol use in people with alcohol use disorder (AUD).
Targeting Cardiovascular Disease Risk Factors May Be Important Across a Lifetime
New findings suggest that all adults, including those over 65, should be mindful of risk factors for cardiovascular disease.
Mutation May Explain Why Some Get More Severe RSV Disease
A mutation in the gene of a white blood cell protein contributes to the severity of respiratory syncytial virus (RSV) infection.
NIH Begins Testing Investigational Zika Vaccine in Humans
NIAID has launched a clinical trial of a vaccine candidate intended to prevent Zika virus infection. The study will evaluate the vaccine’s safety and ability to generate an immune system response.
Study Supports Surgery for Myasthenia Gravis
In a global study of myasthenia gravis, researchers found that surgical removal of an organ called the thymus reduced patients’ weakness and their need for immunosuppressive drugs.
Tapping Crowd-Sourced Data Unearths Trove of Depression Genes
Scientists have discovered 15 genome sites—the first ever—linked to depression in people of European ancestry.
Visual Impairment, Blindness Cases in U.S. Expected to Double by 2050
With the youngest of the baby boomers hitting 65 by 2029, the number of people with visual impairment or blindness in the United States is expected to double to more than 8 million by 2050, according to projections based on the most recent census data and from studies funded by NEI.
NIH-Funded Study Reveals How Differences in Male, Female Brains Emerge
According to new research published in Nature, scientists have determined how these sexually dimorphic (occurring in either males or females) connections arise in the worm nervous system. The research was funded by NINDS.