NIH Researchers Find Potential Genetic Cause of Cushing Syndrome
A small study by researchers at NIH suggests that mutations in the gene CABLES1 may lead to Cushing syndrome, a rare disorder in which the body overproduces the stress hormone cortisol.
Mycobacteria Use Protein to Create Diverse Populations, Avoid Drugs
A single protein allows mycobacteria to generate diverse populations that can avoid TB drugs. The protein may be a target for intervention; blocking it might result in less mycobacterial diversity and shorten TB treatment courses.
Baby Teeth Link Autism and Heavy Metals, Study Suggests
Baby teeth from children with autism contain more toxic lead and less of the essential nutrients zinc and manganese, compared to teeth from children without autism.
Researchers Unlock Regenerative Potential of Cells in Mouse Retina
Cells within an injured mouse eye can be coaxed into regenerating neurons and those new neurons appear to integrate themselves into the eye’s circuitry, new research shows.
Immune System May Mount an Attack in Parkinson’s Disease
A new study suggests that T cells, which help the body’s immune system recognize friend from foe, may play an important role in Parkinson’s disease.
New Imaging Technique Overturns Longstanding Model of DNA Folding
Researchers funded by NIH have developed a new imaging method that visualizes a very different DNA structure, featuring small folds of DNA in close proximity. The study reveals that the DNA-protein structure, known as chromatin, is a much more diverse and flexible chain than previously thought.
Sex Hormone-Sensitive Gene Complex Linked to Premenstrual Mood Disorder
NIH researchers have discovered molecular mechanisms that may underlie a woman’s susceptibility to disabling irritability, sadness and anxiety in the days leading up to her menstrual period.
TCGA Study Identifies Genomic Features of Cervical Cancer
Investigators with the Cancer Genome Atlas (TCGA) Research Network have identified novel genomic and molecular characteristics of cervical cancer that will aid in the sub-classification of the disease and may help target therapies that are most appropriate for each patient.
Parental Obesity Linked to Delays in Child Development, Study Suggests
Children of obese parents may be at risk for developmental delays, according to a study by researchers at NIH.
Experimental Malaria Vaccine Provides Protection Against Multiple Strains
An investigational malaria vaccine has protected a small number of healthy U.S. adults from infection with a malaria strain different from that contained in the vaccine, according to a study published Feb. 21 in the Proceedings of the National Academy of Sciences.