Rapid-Response Immune Cells Are Fully Prepared Before Invasion Strikes
Through the use of powerful genomic techniques, researchers at NIAMS have found that the development of immune cells, called innate lymphoid cells (ILCs), gradually prepares these cells for rapid response to infection.
NIH Creates Atlas of Human Malformation Syndromes
Researchers with NHGRI have collaborated with physicians and medical geneticists around the world to create the Atlas of Human Malformation Syndromes in Diverse Populations. Health care providers can use the new atlas to diagnose diverse patients with inherited diseases.
Ketamine Lifts Depression via a Byproduct of Its Metabolism
A chemical byproduct, or metabolite, created as the body breaks down ketamine likely holds the secret to its rapid antidepressant action, NIH scientists and grantees have discovered.
Mice Study May Lead to Discovery Of Broad-Spectrum Antiviral
After herpesviruses infect a cell, their genomes are assembled into specialized protein structures called nucleosomes. Many cellular enzyme complexes can modulate these structures to either promote or inhibit the progression of infection.
Specialized Mouse Neurons Play a Unique Role in Pain
Researchers from NIH have identified a class of sensory neurons (nerve cells that electrically send and receive messages between the body and brain) that can be activated by stimuli as precise as the pulling of a single hair.
Female Mouse Embryos Remove Male Reproductive Systems
A protein called COUP-TFII determines whether a mouse embryo develops a male reproductive tract, according to researchers at NIH and their colleagues at Baylor College of Medicine.
Scientists Develop Infection Model for Tick-Borne Flaviviruses
NIH scientists have filled a research gap by developing a laboratory model to study ticks that transmit flaviviruses, such as Powassan virus. Powassan virus was implicated in the death of a New York man earlier this year.
Prevention Strategy Benefits Persist After 1-Year Peanut Avoidance
The benefits of regularly consuming peanut-containing foods early in life to prevent the development of peanut allergy persist even after stopping peanut consumption for 1 year, new clinical trial findings show.
Marijuana Use Disorder Is Common, Often Untreated
Marijuana use disorder is common in the United States, is often associated with other substance use disorders, behavioral problems and disability and goes largely untreated, according to a new study conducted by NIAAA.