Harnessing T-Cell ‘Stemness’ Could Enhance Cancer Immunotherapy
A new study led by scientists at NCI sheds light on one way tumors may continue to grow despite the presence of cancer-killing immune cells. The findings, published Mar. 29 in Science, suggest a way to enhance the effectiveness of immunotherapies for cancer treatment.
FDA-Approved Drug Effectively Treats Rare Chronic Immune Disorder
A drug approved to treat a severe form of asthma dramatically improved the health of people with rare chronic immune disorders called hypereosinophilic syndromes (HES) in whom other treatments were ineffective or intolerable.
First-in-Human Trial of a Universal Influenza Vaccine Candidate Begins
The first clinical trial of an innovative universal influenza vaccine candidate is examining the vaccine’s safety and tolerability as well as its ability to induce an immune response in healthy volunteers. Scientists at NIAID developed the experimental vaccine.
Study Finds Ebola Survivors in Liberia Face Ongoing Health Issues
Survivors of Ebola virus disease (EVD) in Liberia had a higher prevalence of certain health issues when compared to a control group of household and community members who did not have a history of EVD.
Tuberculosis Diagnosis in People with HIV Increases Risk of Death Within 10 Years
Among people with HIV in Latin America, those diagnosed with tuberculosis (TB) at an initial clinic visit were about twice as likely to die within 10 years as people not initially diagnosed with TB.
Vitamin D May Protect Against Pollution-Associated Asthma Symptoms in Obese Children
A new study finds vitamin D may be protective among asthmatic obese children living in urban environments with high indoor air pollution.
Rate of Life-Threatening Childbirth Complications Increasing Sharply
Racial and ethnic disparities in severe maternal morbidity—life-threatening maternal complications associated with childbirth—have persisted and increased at high rates among U.S. women.
Results of Trial to Stem Hospital-Acquired Bacterial Infections Published
New findings from a large, randomized clinical trial that compared two infection-control techniques are already being incorporated into practice within the network of U.S. community hospitals where the trial took place.
Study of Brain Energy Patterns Provides New Insights into Alcohol Effects
Assessing the patterns of energy use and neuronal activity simultaneously in the human brain improves our understanding of how alcohol affects the brain.