Patients with Colorectal Cancer Sought

Do you or someone you know have colorectal cancer? Have previous treatments failed? Researchers at the Clinical Center are testing whether pexastimogene devacirepvec (Pexa-Vec), given in combination with durvalumab, will cause tumors to shrink. Pexa-Vec is a vaccine used to help boost the immune system to attack and destroy the cancer cells in patients. Treatments and research procedures are provided at no cost. Travel may be provided. For more information call 800-411-1222 (TTY 800-877-8339) or email prpl@cc.nih.gov. Refer to study 17-C-0092. Read more at https://go.usa.gov/xpvP3.

Women with PCOS Sought

NIDDK seeks women 18-40 with polycystic ovary syndrome (PCOS) to participate in a research study. Researchers are studying a type of body fat called brown fat and the role it plays in how we burn energy. Participation includes taking a medication daily for 4 weeks, 2 overnight inpatient stays for testing and 2 outpatient visits. Compensation is provided. For more information, contact the Clinical Center Office of Patient Recruitment at 866-444-2214 (TTY 800-877-8339) or prpl@cc.nih.gov. Refer to study 17-DK-0054. Read more at https://go.usa.gov/x5Mmj.

Menopause & Mood Study 

A 7-week outpatient study is accepting post-menopausal women ages 45 to 65 who struggled with irritability, anxiety, sadness or depression during perimenopause and had symptoms that improved with the use of hormones. There is no cost to participate. Compensation is provided. To learn more about the study call (301) 496-9576 (TTY 1-866-411-1010) or visit https://go.usa.gov/xPkKB. Refer to study 18-M-0144.