![Beta-galactosidase at 3.2 Å resolution Scientific image of glowing green branches floating in a black background with two orange beams aimed at the red and blue tips.](/sites/nihrecord/files/styles/thumbnail_small/public/2021/October-29/20211029-cvr-Beta-galactosidase.jpg?itok=wIBNRI4U)
On the Cover
This image of beta-galactosidase at 3.2 Å resolution illustrates the differential effect that electron radiation (orange rays) has on different parts of proteins (green) during high-resolution cryo-electron microscopy imaging. Acidic side chains, like glutamate (bottom, red atoms) break down first, before more basic side chains, like histidine (top, blue atoms).
Veronica Falconieri & Sriram Subramaniam, NCI