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NIH Record - 75th Anniversary - National Institutes of Health

Scotto, Former DCEG Biostatistician, Mourned

Joseph Scotto

Joseph Scotto, retired biostatistician and epidemiologist at NCI

Joseph Scotto, retired biostatistician and epidemiologist at the National Cancer Institute, passed away on Aug. 5 at the age of 81. In 1962, following graduation from Columbia University School of Public Health, he joined NCI’s Biostatistics Branch as a commissioned officer in the Public Health Service. He retired in 1992 after 30 years of service.  

During his NCI career, Scotto applied his expertise in statistics toward the development of population-based studies of skin cancer. 

Prior to the 1970s, the descriptive statistics on non-melanoma skin cancer incidence were grossly underestimated due to the reliance on hospital diagnoses, which did not capture most of these cases. 

Scotto took the lead in designing and conducting periodic surveys of skin cancer in parts of the country involved in studies of cancer incidence and mortality. He joined forces with other agencies to measure ground-level ultraviolet radiation (UV)-B exposure in those areas, clarifying the relationship between exposure to UV and risk of skin cancer. These data provided evidence needed to address mounting public health concerns about the thinning of the ozone layer in the atmosphere, a result of certain human-made environmental pollutants.

Together with Dr. Thomas Fears of the Biostatistics Branch, Scotto utilized the trends in skin cancer and UV-B exposure along with satellite data to develop innovative mathematical models to project trends of skin cancer expected from further reduction in the protective ozone layer. The results of these studies are summarized in separate chapters on UV radiation and non-melanoma skin cancer published in the first three editions of the textbook Cancer Epidemiology and Prevention, edited by David Schottenfeld and Joseph F. Fraumeni, Jr.

“Joe’s portfolio of research in non-melanoma skin cancer filled major gaps in our understanding of these extremely common tumors,” said Fraumeni. “His leadership in skin cancer epidemiology, his outgoing personality and his collaborative approach to working with scientists at other agencies, including EPA, NOAA and NASA, have provided a model for evaluating and mitigating threats to public health that may be posed by climate change.” 

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