NIH Record - National Institutes of Health

Volunteers Needed for PKLR Gene Study

NHLBI invites volunteers ages 18-80 of African descent with or without sickle cell trait and people with sickle cell disease to participate in a one-time visit research study. Volunteers will provide blood samples that will be used to look for a link between the PKLR gene and pyruvate kinase protein. The PKLR gene is active in the liver and in the red blood cells and helps to create protein called pyruvate kinase that is essential in normal functioning of the red blood cells. Compensation provided. For more information about study #18-H-0146, call 866-444-2214, email, or visit

Study Needs Volunteers with CLL/SLL

NHLBI researchers need volunteers with chronic lymphocytic leukemia (CLL)/ small lymphocytic lymphoma (SLL) for a vaccine study. Researchers are studying how well the following vaccines work in patients with CLL/SLL malignancies: SHINGRIX and influenza vaccine. If you are currently receiving treatment for CLL/SLL (e.g. ibrutinib, acalabrutinib or venetoclax), you may be eligible to participate. Contact the Clinical Center Office of Patient Recruitment at (866) 444-2214 (TTY users dial 711) or Refer to study #000444-H. Online:

The NIH Record

The NIH Record, founded in 1949, is the biweekly newsletter for employees of the National Institutes of Health.

Published 25 times each year, it comes out on payday Fridays.

Assistant Editor: Eric Bock (link sends e-mail)

Staff Writer: Amber Snyder (link sends e-mail)