Scientists have identified an autoinflammatory disease caused by mutations in the LYN gene, an important regulator of immune responses in health and disease.

A clinical trial testing a freeze-dried, temperature-stable experimental tuberculosis (TB) vaccine in healthy adults found that it was safe and stimulated both antibodies and responses from the cellular arm of the immune system.

Scientists at NIH and Massachusetts General Hospital (MGH) have uncovered a potential new approach against liver cancer that could lead to the development of a new class of anti-cancer drugs.

By using state-of-the-art technology to analyze patterns of behavior in mice with epilepsy, researchers may be able to better study the disorder and identify potential treatments.

A new tool shows promise in helping primary care physicians identify adults with undiagnosed chronic obstructive pulmonary disease (COPD), according to research published in JAMA.

In a small study, researchers used a device that stimulates the spinal cord to restore arm and hand mobility in two stroke patients, allowing them to perform daily life activities, such as using a fork to eat a meal.

Black and Hispanic Americans appear to experience more symptoms and health problems related to long Covid than White people.

In a mouse study, NIH-funded researchers have identified a potential non-hormonal contraceptive that men could take shortly before sexual activity and have fertility restored the next day.

Previous research has suggested that viruses may play a role in certain neurodegenerative diseases. One recent study found a link between Epstein-Barr virus infection and the risk of multiple sclerosis (MS).

A single oral dose of the antibiotic azithromycin can reduce the risk of postpartum sepsis and death among women who deliver vaginally by one-third, based on a large, NIH-funded multi-country clinical trial.