Cognitive Behavioral Therapy Alters Brain Activity in Children with Anxiety
NIH researchers have found that children with anxiety disorders have overactivity in several brain regions.
Switching to Vegan or ‘Keto’ Diets Rapidly Affects Immune System
NIH researchers observed rapid and distinct immune system changes in a small study of people who switched to a vegan or a ketogenic (keto) diet.
Abnormal Proteins Found in Spinal Fluid of People with ALS and Dementia
NIH researchers detected abnormal proteins in the spinal fluid of people with amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), which could help improve diagnosis of these diseases.
Atlas of Placenta May Yield New Clues
An atlas revealing the activity of individual placental cells during childbirth offers insight on what happens at the maternal-fetal interface during term labor, according to an NIH-supported study.
Common Marker of Neurological Diseases May Play Role in Healthy Brains
Researchers have discovered that a protein called phosphorylated α-synuclein, which is associated with several neurodegenerative diseases such as Parkinson’s disease and Lewy body dementia, is also involved in the normal processes of how neurons communicate with each other in a healthy brain.
NIH-Developed HIV Antibodies Protect Animals in Study
Three different HIV antibodies each independently protected monkeys from acquiring simian-HIV (SHIV) in a placebo-controlled proof-of-concept study intended to inform development of a preventive HIV vaccine for people.
Decades after Hypertensive Pregnancy Complications, Effects Linger in Hispanic Women
Hispanic/Latina women with a history of hypertensive disorders of pregnancy (HDP)—conditions marked by high blood pressure during pregnancy—are more likely to have abnormalities in their heart structure and function decades later, compared with women without a history of HDP.
Designing a Safer Antifungal Drug
Fungal infections kill more than 1.5 million people every year. Fungi are developing resistance to some currently available antifungal drugs, and many of the remaining drugs are highly toxic. Researchers are studying ways to reduce the toxicity of one of these drugs, amphotericin B (AmB).
Trial to Test New Drug Regimen for TBM
A trial of a new drug regimen to treat tuberculous meningitis (TBM) has started enrolling adults and adolescents in several countries where tuberculosis (TB) is prevalent.