NIH Record - National Institutes of Health

Research Sheds Light on Link Between Covid-19 and CVD Risk

SARS-CoV-2, the virus that causes Covid-19, can directly infect the arteries of the heart and cause the fatty plaque inside arteries to become highly inflamed, increasing the risk of heart attack and stroke, according to an NIH-funded study.

Investigational Drug Restores Parathyroid Function in Rare Disease

An investigational drug, encaleret, restored calcium levels in people with autosomal dominant hypocalcemia type 1 (ADH1), a rare genetic disorder marked by an imbalance of calcium in the blood and urine. People with ADH1 have abnormally low levels of parathyroid hormone, which regulates blood calcium levels.

New Method Developed to Identify Potential Stroke Therapies

Researchers identified uric acid as a potential therapy to enhance recovery from acute ischemic stroke. In the study, researchers from NIH’s Stroke Preclinical Assessment Network (SPAN) rigorously tested the effectiveness of six novel therapies in reducing ischemic brain injury in rodents, including four FDA-approved drugs to treat other conditions.

Severe Covid-19 May Lead to Long-Term Innate Immune System Changes

Severe Covid-19 may cause long-lasting alterations to the innate immune system, the first line of defense against pathogens, according to a small study funded by NIAID. These changes may help explain why the disease can damage so many different organs and why some people with long Covid have high levels of inflammation throughout the body. The findings were published online in the journal Cell.

The NIH Record

The NIH Record, founded in 1949, is the biweekly newsletter for employees of the National Institutes of Health.

Published 25 times each year, it comes out on payday Fridays.

Editor: Dana Talesnik
Dana.Talesnik@nih.gov

Associate Editor: Patrick Smith
pat.smith@nih.gov

Assistant Editor: Eric Bock
Eric.Bock@nih.gov

Staff Writer: Amber Snyder
Amber.Snyder@nih.gov