Repurposing a Blood Pressure Drug May Prevent Vision Loss in Inherited Blinding Diseases
New studies in rats suggest the drug reserpine, approved in 1955 for high blood pressure, might treat the blinding disease retinitis pigmentosa. No therapy exists for this rare inherited disease, which starts affecting vision from childhood. A report on the studies, conducted at NIH, was published in eLife.
NIH-Funded Study Identifies Potential New Stroke Treatment
In a preclinical study, rodents treated with uric acid showed improved long-term outcomes after acute ischemic stroke. The findings suggest the treatment may work as an add-on therapy to standard stroke treatments in humans. The NIH-funded study was published in Stroke.