NIH Record - National Institutes of Health

NHGRI’s Kastner Named Federal Employee of the Year

Dr. Daniel Kastner
Dr. Daniel Kastner

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Dr. Daniel Kastner, scientific director of the National Human Genome Research Institute, was named the Federal Employee of the Year as part of the 2018 Samuel J. Heyman Service to America Medals program, known as the “Sammies.” Each year, the Sammies pay tribute to America’s dedicated federal workforce, honoring those who have made significant contributions to our country.

Kastner was recognized for his work to uncover the genomic causes of multiple rare and debilitating autoinflammatory diseases and identifying and treating previously undiagnosed illnesses, efforts that have alleviated the suffering of thousands of patients in the United States and around the world.

The nonprofit, nonpartisan Partnership for Public Service presented the award to Kastner at a ceremony in Washington, D.C., on Oct. 2.

“I am surprised, humbled and elated for this acknowledgment,” said Kastner. “Seeing my patients overcome debilitating diseases has been my biggest reward. This Sammie award is just icing on the cake.”

Since 2010, Kastner has served as NHGRI’s scientific director, where he is responsible for encouraging implementation of new genomic technologies, application of new treatments for rare genetic diseases and promotion of research collaborations. Before joining NHGRI, he completed rheumatology training at the National Institute of Arthritis and Musculoskeletal and Skin Diseases and then rose through the NIAMS investigator ranks to become NIAMS clinical director from 2005 to 2010.

Throughout his 33-year career in the federal government, Kastner’s research has focused on understanding the genomic underpinnings of inherited disorders of inflammation and treating patients at the Clinical Center. Inflammation is the body’s response to injury, disease or irritation of the tissues. Kastner and his laboratory have made numerous fundamental advances, such as identifying the gene variant that causes familial Mediterranean fever and discovering the genetic basis for a recurrent fever syndrome named TNF receptor-associated periodic syndrome (TRAPS).

Kastner has won numerous awards and honors, including election to the National Academy of Sciences in 2010 and the Institute of Medicine of the National Academies in 2012. He obtained his A.B. summa cum laude in philosophy from Princeton University and a Ph.D. and M.D. from Baylor College of Medicine.—Kiara Palmer

The NIH Record

The NIH Record, founded in 1949, is the biweekly newsletter for employees of the National Institutes of Health.

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