NIH Upgrades Nephele, Revolutionizes Microbiome Data Analysis
NIAID recently released Nephele 3.0, a significant upgrade to its cloud platform for microbiome data analysis. Building on the success of its predecessor, Nephele 3.0 introduces enhanced features to streamline data management and analysis for researchers worldwide.
Over the past two years, Nephele has processed more than 15,000 jobs for more than 1,800 researchers across 250 institutions. Nephele 3.0 (https://nephele.niaid.nih.gov/) continues to offer robust pipelines for amplicon and metagenomic data processing and analysis, catering to the needs of the microbiome community.
With Nephele 3.0, users can expect improved efficiency, usability and flexibility. The updated platform facilitates easy pipeline job monitoring and seamless data management in the cloud, accommodating larger datasets.
Key enhancements include an expanded My Workspace feature with “My Data” (https://go.nih.gov/hjDIfwM) and “My Jobs” (https://go.nih.gov/2cPfgqv), enabling users to manage data and tasks, monitor status and logs, and view results in one centralized location. Additionally, the platform supports more complex dataset uploads through the website and free transfer with Globus, offering flexibility for further analyses with other Nephele pipelines and MicrobiomeDB.org.
Nephele 3.0 is designed to meet the evolving needs of modern research, particularly with the rise in long read sequencing and the increasing size of big data. It facilitates large-scale, efficient and reproducible data processing and analysis, in a command-line free environment. The platform also provides capabilities for statistical analyses and data visualization, enabling researchers to derive insights and make data-driven decisions.
As users transition to Nephele 3.0, they are encouraged to register for new accounts. In addition to the tutorials and guides on the site, the Nephele support team is available for questions, feedback and suggestions at NepheleSupport@mail.nih.gov.
NIAID remains committed to user support and offers extensive documentation and tutorials to ensure a smooth migration. Stay tuned for upcoming demos and workshops to explore Nephele 3.0’s new capabilities.