Sleep-Disordered Breathing in Early Pregnancy Linked to Diabetes Risk
A small NIH-funded study has linked sleep-disordered breathing in early pregnancy with insulin resistance or difficulty clearing glucose from the blood. The results, which appear in Sleep, strengthen the link between sleep-disordered breathing, which includes pauses or slowing of breathing during sleep, and gestational diabetes.
Viagra May Reduce Risk of Alzheimer’s Disease
NIA-funded researchers have found that people who took the drug sildenafil, sold under the brand names Viagra and Revatio, were less likely to develop Alzheimer’s disease (AD). Sildenafil also enhanced growth and reduced Alzheimer’s biomarkers in cultured human neurons.
SARS-CoV-2 Can Infect Inner Ear Cells
A commonly reported symptom of Covid-19 infection has been loss of taste and smell. NIAID-funded researchers have found another sensory connection: SARS-CoV-2 can infect inner ear cells.
Drug Combination Shows Promise for Children with APL
A clinical trial has found the combination of all-trans retinoic acid, which is a metabolite of vitamin A, and arsenic trioxide is highly effective in children with standard- and high-risk acute promyelocytic leukemia, or APL.
Therapy Improves Survival for Younger People With Cancer
New evidence suggests that adding the targeted therapy ibrutinib (Imbruvica) to a standard chemotherapy regimen can improve how long some younger people with a specific form of diffuse large B-cell lymphoma (DLBCL) live.
Targeted Antibiotic Shows Promise Against Lyme
Researchers found that a neglected antibiotic called hygromycin A selectively kills Borelliella burgdorferi, the bacteria that cause Lyme disease. The antibiotic was able to treat Lyme disease in mice without disrupting the microbiome.
Study Links Sleep Habits, Weight Gain in Babies
Research suggests that newborns can reap some of the same health benefits that others get from consistent, quality shut-eye.
Rare Disease Research: NIH, FDA, Private Sector Collaborate
NIH, FDA, 10 pharmaceutical companies and 5 nonprofit organizations have partnered to accelerate development of gene therapies for the 30 million Americans who suffer from a rare disease.
Could Water Pill Be Treatment for Alzheimer’s?
A commonly available FDA-approved oral diuretic pill may be a potential candidate for an Alzheimer’s disease treatment for those who are at genetic risk, according to findings published in Nature Aging.