Friedman Retires from NHLBI After 33 Years
Dr. Lawrence M. Friedman recently retired after 33 years of government
service, all with NHLBI.
|At his retirement luncheon, Dr. Larry Friedman,
assistant director for ethics and clinical research, NHLBI,
accepts a plaque from Dr. Elizabeth Nabel, NHLBI director.
He held many leadership positions overseeing clinical research.
Most recently, he served as assistant director for ethics and clinical
research and acting deputy director for the institute. He also
served as director of the Division of Epidemiology and Clinical
More than 20 years ago, Friedman coauthored a book titled, Fundamentals
of Clinical Trials, now in its third edition. Currently,
he is co-editor of a book due to be released this summer about
clinical trial monitoring whose working title is Case Studies
in Data Monitoring and has hosted a series of seminars on
the subject. He also has served on the editorial boards of numerous
publications, most recently the Annals of Epidemiology and
Evidence-Based Cardiovascular Medicine.
At Friedman's retirement luncheon, Dr. Nancy Geller, director
of the Office of Biostatistics Research, DECA, called him a major
figure in resolving clinical trial dilemmas, referring to him as
one of NHLBI's "quiet fixers."
From a former boss, Dr. William Harlan, now working as a consultant
to other institutes, to his last, current NHLBI director Dr. Elizabeth
Nabel, everyone agreed on Friedman's achievements and the preeminent
role he played in elevating the quality of standards for clinical
trials both nationally and internationally.
Nabel said, "Larry is a scholar and a gentleman. He is known throughout
the NIH community for his wise counsel and prudent judgment. We
will dearly miss him but look forward to his presence in the NHLBI
in an advisory capacity."
Another speaker, Dr. Yves Rosenberg, noted that Friedman always
placed both the individual research participant and the public
interest at the forefront of studies.
Of his time at NHLBI, Friedman noted, "What made my career here
worthwhile was not only the importance of the NIH mission but also
the opportunity to work with so many people who were dedicated
to accomplishing that mission and were wonderful colleagues."
Friedman earned a B.S in 1964 from Trinity College in Hartford.
He earned an M.D. in 1969 at the University of Pittsburgh Medical
School followed by an internship and residency at Connecticut's
Hartford Hospital. In 1972, he joined the Public Health Service
and began his career in the Clinical Trials Branch, NHLBI. He is
the author or coauthor of more than 100 studies that have appeared
in peer- reviewed journals.
Former NIMH'er Holliday Dies
Anabel "Bunny" Holliday, 70, a former employee
of the National Institute of Mental Health, died at her home
in Laytonsville on Mar. 7.
Holliday graduated from American University and was
retired from NIH, where she served from 1965 to 1995. She was born
in Pennsylvania and started her federal career at Letterkenny Army
Depot in Chambersburg, Pa., where she worked from 1960 to 1965.
Holliday is survived by her daughter Karyn Holliday
of Gaithersburg, her daughter Kathi Davis and son-in-law Jim Davis
of Woodbine, Md., and her long-time companion Craig Easter of Laytonsville.
Memorial contributions may be made to the National
Retinitis Pigmentosa Foundation, Inc., 11350 McCormick Rd. #800,
Hunt Valley, MD 21031-1002.
NCRR's Vaitukaitis Is Named a Senior Advisor
to NIH Director
Dr. Judith Vaitukaitis, director of the National
Center for Research Resources, has been named a senior advisor
on scientific infrastructure and resources to NIH director Dr.
|Dr. Judith Vaitukaitis
"With research becoming more complex, teams of investigators
from diverse scientific fields require more sophisticated research
tools and technologies," said Zerhouni. "In view of these needs,
I have asked Dr. Vaitukaitis to advise me of the critical choices
that will contribute to solving tomorrow's research challenges.
Since 1993, she has provided outstanding leadership, ensuring that
NCRR is a catalyst for discovery for NIH-supported investigations
throughout the nation."
Under Vaitukaitis' leadership from 1993 to 2005,
NCRR's budget almost quadrupled and program areas expanded to include
a broad range of cutting- edge research resources, state-of-the
art technologies and critical biological models of human disease.
"Scientific trends and research needs change at an
astonishing pace, yet effective research resources for addressing
investigators' needs cannot be generated overnight," said Vaitukaitis. "One
of our greatest challenges is to ensure that a lack of resources
does not impede research progress. I hope to be able to offer my
insights on how to track cutting-edge advances and identify emerging
trends across biomedical research so that resources are in place
when they are needed.
"The NCRR portfolio is multifaceted — from
building research capacity at academic institutions to providing
clinical research, biotechnology and comparative medicine resources," Vaitukaitis
continued. "During my time as director, I developed the greatest
admiration for the work and dedication of the NCRR staff. Because
of their commitment, we have been able to go beyond conventional
approaches to find innovative resource solutions for researchers
across the nation."
Prior to her service as NCRR director, Vaitukaitis' extensive
basic research on the mechanisms controlling hormonal action and
metabolism at the cellular level and her clinical research in reproductive
endocrinology led to the development of the first specific pregnancy
test. The pregnancy assay she developed continues to be used in
modified forms as over-the-counter early pregnancy-detection products.
The assay also provides a method for monitoring patients with tumors
that developed from either placental tissue or testicular germ
Previously, Vaitukaitis held positions as NCRR deputy
director and director of the NCRR General Clinical Research Center
(GCRC) Program. Prior to joining NCRR, she was professor of medicine
at Boston University School of Medicine, where she also directed
the GCRC and headed the section on endocrinology and metabolism
at Boston City Hospital.
Dr. Barbara Alving, deputy director of NHLBI and
director of the Women's Health Initiative, will serve as acting
director of NCRR.
HEO Elects Executive Board
NINDS's Marler Wins Feinberg Award
The NIH-Hispanic Employment Organization recently elected its executive
board members for the year 2005. They are (from l) Juan
Mendoza, Nelly Villacreses, Ana
Anders, Richard Farina, Hideko
Takahashi, Ofelia Olivero, Migdalia
Rivera-Goba, Elsa Berenstein and Zhanita
Perez. The organization plays a leadership role in proposing
development of Hispanic-relevant NIH policies, plans, programs
and special initiatives, ensuring that they are sensitive to
issues important to the Hispanic population.
Dr. John Marler, NINDS associate director for
clinical trials, recently received the William M. Feinberg Award
for Excellence in Clinical Stroke from the American Stroke Association.
|Dr. John Marler
The award, which is the association's second highest
honor, recognizes significant achievements in the clinical investigation
and management of stroke. Marler — who served as project
leader for NINDS's tPA stroke trial and Master Agreement for Cerebrovascular
Research, two efforts that led to the approval of the drug tPA
as the first treatment for acute stroke — was recognized
for leading major clinical trials resulting in more effective drug
treatment of stroke.
Marler joined NINDS in 1984 as a medical officer
and health scientist administrator in the extramural Division of
Stroke and Trauma, overseeing the institute's clinical stroke research
program. Currently, he focuses on accelerating the translation
of recent discoveries in neuroscience into treatments for neurological
The award, which was presented at the association's
international stroke conference in New Orleans, is named for a
prominent stroke researcher and American Heart Association volunteer
who made notable contributions to a better understanding of stroke.
to top of page