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Vol. LXII, No. 11
May 28, 2010

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Chai To Speak on Developmental Biology, Craniofacial Malformations

Dr. Yang Chai

On Wednesday, June 9 at 2 p.m., Dr. Yang Chai will deliver a talk titled “Developmental Biology and Prevention and Treatment of Craniofacial Malformations,” in Lipsett Amphitheater, Bldg. 10. His is the second of four talks in this year’s NIDCR Seminar Series “From Basic Research to Therapy—The Latest Frontier.”

Chai has developed cutting-edge molecular tools that have helped uncover the nature of growth factors and signaling pathways that control cell fate in the neural crest. For example, he and his colleagues created genetically engineered mice that allowed them to pinpoint the role of several growth factors that signal neural crest cells to properly form teeth, jaw and palate. Chai will discuss how manipulating these growth factors and their signaling pathways could lead to prevention and treatment of congenital abnormalities of the head and face.

Chai is the George and MaryLou Boone professor of craniofacial biology, director of the Center for Craniofacial Molecular Biology and associate dean of research at the Herman Ostrow School of Dentistry of the University of Southern California. He holds a D.M.D. from Peking University, China, where he also trained in oral and maxillofacial surgery. He earned a Ph.D. in craniofacial biology at USC and conducted postdoctoral training from 1991 to 1994. In 1996, he received his D.D.S. from USC and joined the faculty that year. Chai has received many honors and awards, including several teaching awards. He has also chaired the Gordon Research Conference on craniofacial morphogenesis and tissue regeneration.

Sign language interpretation will be provided. For more information, or for reasonable accommodation, contact Mary Daum, (301) 594-7559, and/or the Federal Relay (1-800-877-8339).

The lecture will be videocast live at


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