Dr. Jennifer Doudna of the University of California, Berkeley, will give the annual NIH Director’s Margaret Pittman Lecture on Wednesday, Mar. 11 at 3 p.m. in Kirschstein Auditorium, Bldg. 45. Her topic is “CRISPR-Cas Genome Surveillance: From Basic Biology to Transformative Technology.” The lecture will be integrated into the 2-day NIH Symposium on RNA Biology being held Mar. 11-12 at Natcher Conference Center.
Doudna is the Li Ka Ching chancellor’s chair in biomedical and health sciences, professor of molecular and cell biology, professor of chemistry and an investigator of the Howard Hughes Medical Institute. She is a member of the National Academy of Sciences, the American Academy of Arts and Sciences, the Institute of Medicine and the National Academy of Inventors. She is a recipient of many awards including the NSF Waterman Award, the FNIH Lurie Prize and most recently the 2015 Breakthrough Prize in Life Sciences (along with Emmanuelle Charpentier) for harnessing an ancient mechanism of bacterial immunity into a powerful and general technology for editing genomes, with wide-ranging implications across biology and medicine.
Doudna will discuss a brief history of CRISPR biology from its initial discovery through the elucidation of the CRISPR-Cas9 enzyme mechanism, providing the foundation for remarkable developments using this technology to modify, regulate or mark genomic loci in a wide variety of cells and organisms.
The annual lecture honors Dr. Margaret Pittman, NIH’s first female lab chief, who made significant contributions to microbiology and vaccine development, particularly in the areas of pertussis and tetanus, during her long career at NIAID.
The lecture is part of the Wednesday Afternoon Lecture series. For more information and reasonable accommodation, call Jacqueline Roberts, (301) 594-6747.