NIEHS will welcome systems biologist and personalized
medicine pioneer Dr. Leroy Hood on Mar. 10
to present the annual Dr. Martin Rodbell Lecture at
11 a.m. in Rodbell Auditorium, Bldg. 101. Hood will
explore “Systems Medicine and Proactive P4 Medicine:
Catalyzing a Revolution in Health Care.”
Hood is founder and president of the Institute for
Systems Biology, a nonprofit biomedical research
organization based in Seattle. One of the central concepts
at ISB is a predictive, personalized, preventive
and participatory approach to medicine, or P4 medicine. ISB describes this
approach as a systems or holistic approach that uses new computational and
mathematical tools to analyze the enormous amounts of molecular, cellular,
phenotypic and medical data that now can be generated for each individual.
By viewing medicine as an informational science, P4 medicine will draw on an
understanding of the networks underlying health and disease. “It will represent
a network of networks—genetic networks, molecular networks, cellular
networks, tissue networks, individual networks, population networks and
social networks,” Hood has said.
In addition to publishing 750 papers, Hood holds 36 patents and 17 honorary
degrees and has founded or co-founded 15 biotechnology companies. He
is one of only 15 individuals elected to all three National Academies—the
National Academy of Science, the National Academy of Engineering and the
Institute of Medicine.
The lecture honors former NIEHS scientific director Dr. Martin Rodbell, who
shared the 1994 Nobel Prize in physiology or medicine with Dr. Alfred Gilman
for the discovery of G-proteins, signal transducers that transmit and modulate
signals in cells to control fundamental life processes.